Chlorine in PDB 5bpm: Crystal Structure of Unhydrolyzed Atp Bound Human HSP70 Nbd Double Mutant E268Q+R272K.

The structure of Crystal Structure of Unhydrolyzed Atp Bound Human HSP70 Nbd Double Mutant E268Q+R272K., PDB code: 5bpm was solved by D.Narayanan, R.A.Engh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.08 / 1.83
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.466, 64.278, 144.860, 90.00, 90.00, 90.00
R / Rfree (%)	17.1 / 22.8

The structure of Crystal Structure of Unhydrolyzed Atp Bound Human HSP70 Nbd Double Mutant E268Q+R272K. also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Sodium	(Na)	1 atom

The binding sites of Chlorine atom in the Crystal Structure of Unhydrolyzed Atp Bound Human HSP70 Nbd Double Mutant E268Q+R272K. (pdb code 5bpm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Unhydrolyzed Atp Bound Human HSP70 Nbd Double Mutant E268Q+R272K., PDB code: 5bpm:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Unhydrolyzed Atp Bound Human HSP70 Nbd Double Mutant E268Q+R272K.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Unhydrolyzed Atp Bound Human HSP70 Nbd Double Mutant E268Q+R272K. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:21.1 occ:1.00 HZ2 A:LYS126 2.4 27.4 1.0 H A:ASP32 2.5 25.7 1.0 HB2 A:ASN31 2.6 20.7 1.0 HE22 A:GLN33 2.7 22.9 1.0 HB2 A:ASP32 2.9 17.6 1.0 HD2 A:LYS126 2.9 30.9 1.0 O A:HOH763 3.1 14.9 1.0 NZ A:LYS126 3.2 22.8 1.0 N A:ASP32 3.3 21.4 1.0 NE2 A:GLN33 3.5 19.1 1.0 HZ3 A:LYS126 3.5 27.4 1.0 CB A:ASN31 3.5 17.3 1.0 CB A:ASP32 3.6 14.7 1.0 HD11 A:ILE130 3.7 24.7 1.0 HG12 A:ILE130 3.7 26.8 1.0 HZ1 A:LYS126 3.7 27.4 1.0 CD A:LYS126 3.8 25.7 1.0 CG A:ASP32 3.8 36.3 1.0 O A:HOH731 3.8 42.0 1.0 CE A:LYS126 3.9 24.8 1.0 CG A:ASN31 3.9 22.4 1.0 HE3 A:LYS126 3.9 29.8 1.0 HE21 A:GLN33 4.0 22.9 1.0 CA A:ASP32 4.1 15.8 1.0 O A:HOH632 4.1 30.3 1.0 OE1 A:GLN33 4.1 27.7 1.0 H A:GLN33 4.1 20.2 1.0 O A:HOH725 4.1 16.1 1.0 HB3 A:ASN31 4.1 20.7 1.0 HD3 A:LYS126 4.2 30.9 1.0 HD22 A:ASN31 4.2 26.0 1.0 HG13 A:ILE130 4.2 26.8 1.0 OD1 A:ASP32 4.2 33.8 1.0 CD A:GLN33 4.2 27.0 1.0 OD2 A:ASP32 4.2 37.6 1.0 ND2 A:ASN31 4.2 21.6 1.0 CG1 A:ILE130 4.3 22.3 1.0 C A:ASN31 4.3 21.2 1.0 CA A:ASN31 4.3 17.0 1.0 CD1 A:ILE130 4.4 20.6 1.0 HA A:ASN31 4.4 20.4 1.0 OD1 A:ASN31 4.4 14.8 1.0 HB3 A:ASP32 4.4 17.6 1.0 HD21 A:ASN31 4.7 26.0 1.0 HD13 A:ILE130 4.8 24.7 1.0 N A:GLN33 4.8 16.8 1.0 HE2 A:LYS126 4.8 29.8 1.0 HA A:ASP32 4.8 19.0 1.0 O A:HOH661 4.8 24.6 1.0 C A:ASP32 4.9 23.8 1.0 CG A:LYS126 4.9 22.4 1.0 HB2 A:ASP53 5.0 23.9 1.0 HG2 A:LYS126 5.0 26.8 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Unhydrolyzed Atp Bound Human HSP70 Nbd Double Mutant E268Q+R272K.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Unhydrolyzed Atp Bound Human HSP70 Nbd Double Mutant E268Q+R272K. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl405 b:39.2 occ:1.00 H A:ILE51 2.6 17.4 1.0 HA A:LEU50 3.2 21.8 1.0 O A:HOH863 3.2 38.0 1.0 HZ1 A:LYS126 3.3 27.4 1.0 HB3 A:ALA54 3.3 19.6 1.0 N A:ILE51 3.4 14.5 1.0 O A:ILE51 3.7 17.2 1.0 O A:HOH725 3.9 16.1 1.0 HB2 A:ALA54 4.0 19.6 1.0 HD12 A:ILE51 4.0 36.4 1.0 HB A:ILE51 4.0 16.4 1.0 CB A:ALA54 4.0 16.3 1.0 CA A:LEU50 4.1 18.1 1.0 NZ A:LYS126 4.1 22.8 1.0 HB3 A:LEU50 4.1 19.3 1.0 HD23 A:LEU50 4.2 25.2 1.0 HE3 A:LYS126 4.2 29.8 1.0 HE2 A:LYS126 4.2 29.8 1.0 C A:LEU50 4.2 17.4 1.0 HD22 A:LEU50 4.3 25.2 1.0 HB1 A:ALA54 4.3 19.6 1.0 CA A:ILE51 4.3 12.8 1.0 CE A:LYS126 4.4 24.8 1.0 C A:ILE51 4.4 17.6 1.0 O A:ARG49 4.6 17.9 1.0 HZ2 A:LYS126 4.6 27.4 1.0 HZ3 A:LYS126 4.6 27.4 1.0 CB A:LEU50 4.6 16.1 1.0 CB A:ILE51 4.6 13.7 1.0 CD2 A:LEU50 4.7 21.0 1.0 O A:HOH632 4.7 30.3 1.0 HD13 A:ILE51 4.7 36.4 1.0 CD1 A:ILE51 4.8 30.3 1.0 O A:HOH731 4.8 42.0 1.0 H A:ALA54 5.0 16.6 1.0

D.Narayanan, A.Pflug, T.Christopeit, P.Kyomuhendo, R.A.Engh. Nucleotide Binding to Variants of the HSP70-Nbd. To Be Published.