Chlorine in PDB 5c6b: Crystal Structure of Prefusion-Stabilized Rsv F Variant Sc-Tm

The structure of Crystal Structure of Prefusion-Stabilized Rsv F Variant Sc-Tm, PDB code: 5c6b was solved by J.S.Mclellan, J.P.M.Langedijk, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.95 / 2.40
Space group	P 41 3 2
Cell size a, b, c (Å), α, β, γ (°)	168.200, 168.200, 168.200, 90.00, 90.00, 90.00
R / Rfree (%)	17.8 / 21.1

The binding sites of Chlorine atom in the Crystal Structure of Prefusion-Stabilized Rsv F Variant Sc-Tm (pdb code 5c6b). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Prefusion-Stabilized Rsv F Variant Sc-Tm, PDB code: 5c6b:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Prefusion-Stabilized Rsv F Variant Sc-Tm


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Prefusion-Stabilized Rsv F Variant Sc-Tm within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl606 b:51.9 occ:1.00 N F:TYR458 3.3 35.2 1.0 O F:HOH788 3.4 33.6 1.0 CD1 F:TYR458 3.7 28.7 1.0 CB F:TYR458 3.7 35.9 1.0 O F:LEU456 4.0 38.2 1.0 CA F:TYR458 4.1 37.4 1.0 CG F:TYR458 4.2 39.0 1.0 C F:TYR457 4.2 38.5 1.0 CA F:TYR457 4.2 37.5 1.0 O F:TYR458 4.6 31.1 1.0 CE1 F:TYR458 4.8 31.6 1.0 C F:TYR458 4.8 32.5 1.0 C F:LEU456 5.0 36.0 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Prefusion-Stabilized Rsv F Variant Sc-Tm


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Prefusion-Stabilized Rsv F Variant Sc-Tm within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl607 b:57.0 occ:0.50 N F:ILE217 3.2 49.4 1.0 CA F:ASN216 3.6 60.3 1.0 C F:ASN216 3.8 58.0 1.0 CE F:LYS75 3.9 50.9 1.0 CB F:ASN216 3.9 61.1 1.0 CG2 F:ILE217 3.9 51.6 1.0 CB F:ILE217 4.0 51.6 1.0 CA F:ILE217 4.2 50.7 1.0 CD F:LYS75 4.4 46.3 1.0 OE2 F:GLU218 4.4 58.8 1.0 O F:PRO215 4.8 61.3 1.0 N F:ASN216 4.8 61.2 1.0 NZ F:LYS75 5.0 58.6 1.0

A.Krarup, D.Truan, P.Furmanova-Hollenstein, L.Bogaert, P.Bouchier, I.J.Bisschop, M.N.Widjojoatmodjo, R.Zahn, H.Schuitemaker, J.S.Mclellan, J.P.Langedijk. A Highly Stable Prefusion Rsv F Vaccine Derived From Structural Analysis of the Fusion Mechanism. Nat Commun V. 6 8143 2015.
ISSN: ESSN 2041-1723
PubMed: 26333350
DOI: 10.1038/NCOMMS9143