Chlorine in PDB 5c79: pH Domain of ASAP1 in Complex with DIC4-Ptdins(4,5)P2

The structure of pH Domain of ASAP1 in Complex with DIC4-Ptdins(4,5)P2, PDB code: 5c79 was solved by D.Xia, W.K.Tang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.21 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	37.543, 64.697, 44.428, 90.00, 95.63, 90.00
R / Rfree (%)	19.8 / 23.3

The binding sites of Chlorine atom in the pH Domain of ASAP1 in Complex with DIC4-Ptdins(4,5)P2 (pdb code 5c79). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the pH Domain of ASAP1 in Complex with DIC4-Ptdins(4,5)P2, PDB code: 5c79:

Chlorine binding site 1 out of 1 in the pH Domain of ASAP1 in Complex with DIC4-Ptdins(4,5)P2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of pH Domain of ASAP1 in Complex with DIC4-Ptdins(4,5)P2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl501 b:53.1 occ:1.00 O B:CYS388 2.9 19.4 1.0 O B:LEU386 3.2 22.8 1.0 C B:CYS388 3.5 19.6 1.0 NZ B:LYS430 3.5 24.2 1.0 N B:CYS388 3.7 20.9 1.0 C B:THR387 3.8 21.5 1.0 OE1 B:GLN389 3.8 24.4 1.0 CA B:THR387 3.9 21.3 1.0 C B:LEU386 4.0 20.8 1.0 CA B:CYS388 4.1 21.0 1.0 CE B:LYS430 4.2 24.4 1.0 N B:GLN389 4.3 18.5 1.0 N B:THR387 4.3 19.7 1.0 CB B:GLN389 4.4 20.1 1.0 O B:THR387 4.5 21.9 1.0 CA B:GLN389 4.5 20.3 1.0 CD B:GLN389 4.8 24.1 1.0 O B:LEU385 4.9 17.4 1.0

X.Jian, W.K.Tang, P.Zhai, N.S.Roy, R.Luo, J.M.Gruschus, M.E.Yohe, P.W.Chen, Y.Li, R.A.Byrd, D.Xia, P.A.Randazzo. Molecular Basis For Cooperative Binding of Anionic Phospholipids to the pH Domain of the Arf Gap ASAP1. Structure V. 23 1977 2015.
ISSN: ISSN 0969-2126
PubMed: 26365802
DOI: 10.1016/J.STR.2015.08.008