Chlorine in PDB 5cmk: Crystal Structure of the GLUK2EM Lbd Dimer Assembly Complex with Glutamate and LY466195

Protein crystallography data

The structure of Crystal Structure of the GLUK2EM Lbd Dimer Assembly Complex with Glutamate and LY466195, PDB code: 5cmk was solved by S.Chittori, M.L.Mayer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.86 / 1.80
Space group P 61 2 2
Cell size a, b, c (Å), α, β, γ (°) 102.759, 102.759, 281.992, 90.00, 90.00, 120.00
R / Rfree (%) 16.4 / 18.7

Other elements in 5cmk:

The structure of Crystal Structure of the GLUK2EM Lbd Dimer Assembly Complex with Glutamate and LY466195 also contains other interesting chemical elements:

Fluorine (F) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the GLUK2EM Lbd Dimer Assembly Complex with Glutamate and LY466195 (pdb code 5cmk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the GLUK2EM Lbd Dimer Assembly Complex with Glutamate and LY466195, PDB code: 5cmk:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 5cmk

Go back to Chlorine Binding Sites List in 5cmk
Chlorine binding site 1 out of 2 in the Crystal Structure of the GLUK2EM Lbd Dimer Assembly Complex with Glutamate and LY466195


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the GLUK2EM Lbd Dimer Assembly Complex with Glutamate and LY466195 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl303

b:18.7
occ:0.83
HZ2 A:LYS104 2.3 17.5 1.0
HZ2 B:LYS104 2.3 19.3 1.0
O B:HOH468 2.9 31.2 1.0
O A:HOH434 3.0 29.5 1.0
NZ A:LYS104 3.1 14.6 1.0
NZ B:LYS104 3.2 16.1 1.0
HG3 A:LYS104 3.3 20.5 1.0
HG3 B:LYS104 3.3 20.5 1.0
HZ1 A:LYS104 3.3 17.5 1.0
HZ1 B:LYS104 3.3 19.3 1.0
HG2 A:LYS104 3.5 20.5 1.0
HZ3 A:LYS104 3.5 17.5 1.0
HG2 B:LYS104 3.5 20.5 1.0
HZ3 B:LYS104 3.6 19.3 1.0
HH11 A:ARG228 3.6 51.1 1.0
CG A:LYS104 3.8 17.1 1.0
HD3 A:ARG228 3.8 40.8 1.0
NH1 A:ARG228 3.9 42.6 1.0
CG B:LYS104 3.9 17.1 1.0
HH11 B:ARG228 3.9 50.0 1.0
HD3 B:ARG228 3.9 39.8 1.0
HG1 A:THR232 3.9 16.1 1.0
NH1 B:ARG228 3.9 41.6 1.0
HE3 B:LYS104 4.0 19.9 1.0
HG1 B:THR232 4.0 17.6 1.0
HH12 A:ARG228 4.0 51.1 1.0
O A:PHE102 4.1 13.2 1.0
CE B:LYS104 4.1 16.6 1.0
HH12 B:ARG228 4.1 50.0 1.0
CE A:LYS104 4.2 15.9 1.0
O B:PHE102 4.2 12.1 1.0
HE3 A:LYS104 4.2 19.1 1.0
CZ B:ARG228 4.3 41.1 1.0
CZ A:ARG228 4.4 40.5 1.0
H A:LYS104 4.5 13.9 1.0
HA A:LYS104 4.5 16.1 1.0
H B:LYS104 4.6 14.6 1.0
N A:LYS104 4.6 11.6 1.0
NE B:ARG228 4.6 40.6 1.0
CD A:ARG228 4.6 34.0 1.0
HA B:LYS104 4.6 16.4 1.0
CD B:LYS104 4.6 17.6 1.0
CD B:ARG228 4.6 33.2 1.0
CD A:LYS104 4.6 17.0 1.0
N B:LYS104 4.6 12.2 1.0
HG21 B:THR232 4.7 18.2 1.0
OG1 A:THR232 4.7 13.4 1.0
NE A:ARG228 4.7 40.3 1.0
HD2 A:ARG228 4.8 40.8 1.0
OG1 B:THR232 4.8 14.6 1.0
C A:SER103 4.8 11.5 1.0
HA A:SER103 4.8 15.2 1.0
HD2 B:ARG228 4.8 39.8 1.0
HG21 A:THR232 4.8 14.9 1.0
NH2 B:ARG228 4.9 39.4 1.0
HA B:SER103 4.9 15.6 1.0
CA A:LYS104 4.9 13.5 1.0
HE2 B:LYS104 4.9 19.9 1.0
C B:SER103 5.0 12.5 1.0
HE2 A:LYS104 5.0 19.1 1.0
CA B:LYS104 5.0 13.6 1.0

Chlorine binding site 2 out of 2 in 5cmk

Go back to Chlorine Binding Sites List in 5cmk
Chlorine binding site 2 out of 2 in the Crystal Structure of the GLUK2EM Lbd Dimer Assembly Complex with Glutamate and LY466195


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the GLUK2EM Lbd Dimer Assembly Complex with Glutamate and LY466195 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl305

b:50.9
occ:0.87
HA B:ARG4 3.0 34.4 1.0
OD1 B:ASN3 3.4 75.9 1.0
O B:HOH699 3.5 46.6 1.0
HB2 B:ARG4 3.6 37.8 1.0
CA B:ARG4 3.8 28.6 1.0
N B:ARG4 4.0 29.3 1.0
CB B:ARG4 4.1 31.5 1.0
HG3 B:ARG4 4.1 39.3 1.0
H B:ARG4 4.2 35.2 1.0
CG B:ASN3 4.5 74.0 1.0
C B:ASN3 4.5 33.3 1.0
O B:ASN3 4.6 26.7 1.0
CG B:ARG4 4.6 32.8 1.0
H B:SER5 4.7 25.3 1.0
HD21 B:ASN3 4.9 99.7 1.0
HB3 B:ARG4 5.0 37.8 1.0

Reference:

J.R.Meyerson, S.Chittori, A.Merk, P.Rao, T.H.Han, M.Serpe, M.L.Mayer, S.Subramaniam. Structural Basis of Kainate Subtype Glutamate Receptor Desensitization. Nature V. 537 567 2016.
ISSN: ESSN 1476-4687
PubMed: 27580033
DOI: 10.1038/NATURE19352
Page generated: Sat Dec 12 11:35:31 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy