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Atomistry » Chlorine » PDB 5cna-5cu2 » 5ctp | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5cna-5cu2 » 5ctp » |
Chlorine in PDB 5ctp: Crystal Structure of CK2ALPHA with N-(3-(3-Chloro-4-(Phenyl) Benzylamino)Propyl)Acetamide BoundEnzymatic activity of Crystal Structure of CK2ALPHA with N-(3-(3-Chloro-4-(Phenyl) Benzylamino)Propyl)Acetamide Bound
All present enzymatic activity of Crystal Structure of CK2ALPHA with N-(3-(3-Chloro-4-(Phenyl) Benzylamino)Propyl)Acetamide Bound:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of CK2ALPHA with N-(3-(3-Chloro-4-(Phenyl) Benzylamino)Propyl)Acetamide Bound, PDB code: 5ctp
was solved by
P.Brear,
C.De Fusco,
K.H.Georgiou,
D.Spring,
M.Hyvonen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of CK2ALPHA with N-(3-(3-Chloro-4-(Phenyl) Benzylamino)Propyl)Acetamide Bound
(pdb code 5ctp). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of CK2ALPHA with N-(3-(3-Chloro-4-(Phenyl) Benzylamino)Propyl)Acetamide Bound, PDB code: 5ctp: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 5ctpGo back to Chlorine Binding Sites List in 5ctp
Chlorine binding site 1 out
of 3 in the Crystal Structure of CK2ALPHA with N-(3-(3-Chloro-4-(Phenyl) Benzylamino)Propyl)Acetamide Bound
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 5ctpGo back to Chlorine Binding Sites List in 5ctp
Chlorine binding site 2 out
of 3 in the Crystal Structure of CK2ALPHA with N-(3-(3-Chloro-4-(Phenyl) Benzylamino)Propyl)Acetamide Bound
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 5ctpGo back to Chlorine Binding Sites List in 5ctp
Chlorine binding site 3 out
of 3 in the Crystal Structure of CK2ALPHA with N-(3-(3-Chloro-4-(Phenyl) Benzylamino)Propyl)Acetamide Bound
Mono view Stereo pair view
Reference:
C.De Fusco,
P.Brear,
J.Iegre,
K.H.Georgiou,
H.F.Sore,
M.Hyvonen,
D.R.Spring.
A Fragment-Based Approach Leading to the Discovery of A Novel Binding Site and the Selective CK2 Inhibitor CAM4066. Bioorg. Med. Chem. V. 25 3471 2017.
Page generated: Sat Dec 12 11:35:58 2020
ISSN: ESSN 1464-3391 PubMed: 28495381 DOI: 10.1016/J.BMC.2017.04.037 |
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