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Atomistry » Chlorine » PDB 5cu3-5d0t » 5czx | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5cu3-5d0t » 5czx » |
Chlorine in PDB 5czx: Crystal Structure of NOTCH3 Nrr in Complex with 20358 FabProtein crystallography data
The structure of Crystal Structure of NOTCH3 Nrr in Complex with 20358 Fab, PDB code: 5czx
was solved by
T.Hu,
C.Fryer,
R.Chopra,
K.Clark,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5czx:
The structure of Crystal Structure of NOTCH3 Nrr in Complex with 20358 Fab also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of NOTCH3 Nrr in Complex with 20358 Fab
(pdb code 5czx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of NOTCH3 Nrr in Complex with 20358 Fab, PDB code: 5czx: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 5czxGo back to Chlorine Binding Sites List in 5czx
Chlorine binding site 1 out
of 3 in the Crystal Structure of NOTCH3 Nrr in Complex with 20358 Fab
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 5czxGo back to Chlorine Binding Sites List in 5czx
Chlorine binding site 2 out
of 3 in the Crystal Structure of NOTCH3 Nrr in Complex with 20358 Fab
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 5czxGo back to Chlorine Binding Sites List in 5czx
Chlorine binding site 3 out
of 3 in the Crystal Structure of NOTCH3 Nrr in Complex with 20358 Fab
Mono view Stereo pair view
Reference:
P.Bernasconi-Elias,
T.Hu,
D.Jenkins,
B.Firestone,
S.Gans,
E.Kurth,
P.Capodieci,
J.Deplazes-Lauber,
K.Petropoulos,
P.Thiel,
D.Ponsel,
S.Hee Choi,
P.Lemotte,
A.London,
M.Goetcshkes,
E.Nolin,
M.D.Jones,
K.Slocum,
M.J.Kluk,
D.M.Weinstock,
A.Christodoulou,
O.Weinberg,
J.Jaehrling,
S.A.Ettenberg,
A.Buckler,
S.C.Blacklow,
J.C.Aster,
C.J.Fryer.
Characterization of Activating Mutations of NOTCH3 in T-Cell Acute Lymphoblastic Leukemia and Anti-Leukemic Activity of NOTCH3 Inhibitory Antibodies. Oncogene V. 35 6077 2016.
Page generated: Sat Dec 12 11:37:02 2020
ISSN: ISSN 0950-9232 PubMed: 27157619 DOI: 10.1038/ONC.2016.133 |
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