Chlorine in PDB 5dgg: Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila

The structure of Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila, PDB code: 5dgg was solved by J.Osipiuk, E.Evdokimova, V.Yim, A.Joachimiak, A.Ensminger, A.Savchenko, Midwest Center For Structural Genomics (Mcsg), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.30 / 1.93
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	49.085, 56.564, 121.994, 90.00, 90.00, 90.00
R / Rfree (%)	17.6 / 21.8

The binding sites of Chlorine atom in the Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila (pdb code 5dgg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila, PDB code: 5dgg:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:31.6 occ:1.00 O A:HOH502 3.1 40.8 1.0 O A:HOH575 3.1 37.5 1.0 O A:HOH547 3.2 29.3 1.0 N A:LYS243 3.3 31.4 1.0 CA A:PRO242 3.6 28.8 1.0 CB A:PRO242 3.7 29.4 1.0 CG A:LEU282 3.8 26.2 1.0 CD2 A:LEU282 3.8 28.0 1.0 C A:PRO242 4.0 29.4 1.0 CG A:LYS243 4.0 38.1 1.0 NZ A:LYS262 4.0 47.5 1.0 CD1 A:LEU282 4.1 26.2 1.0 CD1 A:TYR259 4.1 24.9 1.0 CB A:LYS243 4.2 34.8 1.0 CE1 A:TYR259 4.3 27.1 1.0 CA A:LYS243 4.4 32.8 1.0 CD A:LYS262 4.7 39.2 1.0 O A:LEU282 4.7 29.2 1.0 CD A:LYS243 4.8 43.5 1.0 N A:PRO242 4.8 26.6 1.0 CA A:ASP283 4.9 33.5 1.0 OD1 A:ASP283 4.9 41.7 1.0 CE A:LYS262 4.9 44.2 1.0 O A:HOH569 4.9 47.6 1.0 C A:LEU282 5.0 29.2 1.0

Chlorine binding site 2 out of 3 in the Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:45.5 occ:1.00 N A:TYR250 3.4 33.1 1.0 CB A:ALA249 3.6 38.7 1.0 N A:ALA249 3.7 34.8 1.0 CB A:TYR250 3.9 34.6 1.0 CA A:ALA249 4.0 35.6 1.0 CD2 A:TYR250 4.1 37.3 1.0 CA A:TYR250 4.2 33.5 1.0 C A:ALA249 4.2 34.0 1.0 CG A:TYR250 4.5 35.9 1.0 O A:HOH571 4.5 50.6 1.0 C A:ASP248 4.6 35.8 1.0 CB A:ASP248 4.9 39.5 1.0

Chlorine binding site 3 out of 3 in the Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Central Domain of Uncharacterized LPG1148 Protein From Legionella Pneumophila within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl501 b:28.5 occ:1.00 O B:HOH609 2.9 42.5 1.0 O B:HOH655 3.2 38.0 1.0 N B:LYS243 3.2 27.9 1.0 O B:HOH625 3.3 27.1 1.0 CA B:PRO242 3.6 26.9 1.0 CG B:LEU282 3.8 27.4 1.0 C B:PRO242 3.9 27.3 1.0 CB B:PRO242 3.9 27.4 1.0 CD2 B:LEU282 4.0 27.4 1.0 CG B:LYS243 4.0 39.4 1.0 CB B:LYS243 4.1 35.1 1.0 CD1 B:TYR259 4.1 23.5 1.0 CD1 B:LEU282 4.1 27.6 1.0 CA B:LYS243 4.3 30.7 1.0 CE1 B:TYR259 4.3 24.5 1.0 CD B:LYS243 4.7 43.3 1.0 NZ B:LYS262 4.7 44.7 1.0 O B:LEU282 4.7 29.3 1.0 CD B:LYS262 4.8 36.3 1.0 CE B:LYS262 4.8 42.9 1.0 CA B:ASP283 4.8 32.8 1.0 N B:PRO242 4.9 24.9 1.0 O B:GLY241 4.9 24.1 1.0 C B:LEU282 5.0 28.5 1.0

M.L.Urbanus, A.T.Quaile, P.J.Stogios, M.Morar, C.Rao, R.Di Leo, E.Evdokimova, M.Lam, C.Oatway, M.E.Cuff, J.Osipiuk, K.Michalska, B.P.Nocek, M.Taipale, A.Savchenko, A.W.Ensminger. Diverse Mechanisms of Metaeffector Activity in An Intracellular Bacterial Pathogen, Legionella Pneumophila. Mol. Syst. Biol. V. 12 893 2016.
ISSN: ESSN 1744-4292
PubMed: 27986836
DOI: 10.15252/MSB.20167381