Chlorine in PDB 5dh3: Crystal Structure of MST2 in Complex with Xmu-Mp-1

All present enzymatic activity of Crystal Structure of MST2 in Complex with Xmu-Mp-1:
2.7.11.1;

The structure of Crystal Structure of MST2 in Complex with Xmu-Mp-1, PDB code: 5dh3 was solved by L.L.Kong, C.H.Yun, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.22 / 2.47
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	89.871, 98.462, 166.771, 90.00, 90.00, 90.00
R / Rfree (%)	21.1 / 24.7

The binding sites of Chlorine atom in the Crystal Structure of MST2 in Complex with Xmu-Mp-1 (pdb code 5dh3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of MST2 in Complex with Xmu-Mp-1, PDB code: 5dh3:

Chlorine binding site 1 out of 1 in the Crystal Structure of MST2 in Complex with Xmu-Mp-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of MST2 in Complex with Xmu-Mp-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:0.6 occ:1.00 NZ A:LYS132 3.1 67.2 1.0 NZ A:LYS128 3.8 72.4 1.0 CE A:LYS128 4.0 63.2 1.0 CE A:LYS132 4.1 57.7 1.0

F.Fan, Z.He, L.L.Kong, Q.Chen, Q.Yuan, S.Zhang, J.Ye, H.Liu, X.Sun, J.Geng, L.Yuan, L.Hong, C.Xiao, W.Zhang, X.Sun, Y.Li, P.Wang, L.Huang, X.Wu, Z.Ji, Q.Wu, N.S.Xia, N.S.Gray, L.Chen, C.H.Yun, X.Deng, D.Zhou. Pharmacological Targeting of Kinases MST1 and MST2 Augments Tissue Repair and Regeneration Sci Transl Med V. 8 RA108 2016.
ISSN: ESSN 1946-6242
PubMed: 27535619
DOI: 10.1126/SCITRANSLMED.AAF2304