Chlorine in PDB 5ed7: Crystal Structure of Hsv-1 UL21 C-Terminal Domain

The structure of Crystal Structure of Hsv-1 UL21 C-Terminal Domain, PDB code: 5ed7 was solved by C.M.Metrick, E.E.Heldwein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	51.98 / 2.72
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	54.273, 54.273, 180.757, 90.00, 90.00, 90.00
R / Rfree (%)	21.8 / 23.4

The binding sites of Chlorine atom in the Crystal Structure of Hsv-1 UL21 C-Terminal Domain (pdb code 5ed7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Crystal Structure of Hsv-1 UL21 C-Terminal Domain, PDB code: 5ed7:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in the Crystal Structure of Hsv-1 UL21 C-Terminal Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Hsv-1 UL21 C-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:86.6 occ:1.00 N A:LEU284 3.4 55.2 1.0 CA A:THR283 3.7 59.1 1.0 CB A:THR283 3.9 53.8 1.0 C A:THR283 4.1 57.0 1.0 CB A:LEU284 4.3 54.3 1.0 CG2 A:THR283 4.4 53.4 1.0 CA A:LEU284 4.4 51.6 1.0 CG A:LEU284 4.6 53.0 1.0 CE1 A:TYR353 4.8 52.7 1.0 O A:PRO282 4.9 65.8 1.0 OH A:TYR353 4.9 53.8 1.0 N A:THR283 4.9 62.6 1.0

Chlorine binding site 2 out of 6 in the Crystal Structure of Hsv-1 UL21 C-Terminal Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Hsv-1 UL21 C-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl602 b:83.2 occ:1.00 N A:ALA329 3.9 95.8 1.0 CD A:PRO344 4.2 65.9 1.0 CG A:PRO344 4.2 64.6 1.0 CA A:SER328 4.4 87.0 1.0 CB A:ALA329 4.4 99.0 1.0 C A:SER328 4.6 93.5 1.0 CA A:ALA329 4.8 98.5 1.0 CB A:SER328 4.8 88.5 1.0 CB A:PRO344 5.0 63.6 1.0

Chlorine binding site 3 out of 6 in the Crystal Structure of Hsv-1 UL21 C-Terminal Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Hsv-1 UL21 C-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl603 b:95.5 occ:1.00 NH1 A:ARG443 3.3 70.8 1.0 NH2 A:ARG443 3.7 69.7 1.0 OG A:SER441 3.9 81.1 1.0 CZ A:ARG443 3.9 66.9 1.0 CB A:SER441 4.4 71.0 1.0 CA A:SER441 4.5 67.2 1.0

Chlorine binding site 4 out of 6 in the Crystal Structure of Hsv-1 UL21 C-Terminal Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Hsv-1 UL21 C-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl604 b:0.4 occ:1.00 O A:LEU416 3.3 0.6 1.0 CD1 A:PHE414 3.7 0.5 1.0 N A:LEU416 3.9 0.8 1.0 CB A:PHE414 4.0 0.2 1.0 CB A:LEU416 4.0 0.8 1.0 C A:LEU416 4.2 0.8 1.0 CA A:PHE414 4.2 0.3 1.0 CA A:LEU416 4.3 0.5 1.0 CG A:PHE414 4.4 0.2 1.0 N A:ASP415 4.4 0.7 1.0 C A:PHE414 4.6 0.1 1.0 CE1 A:PHE414 4.8 0.8 1.0

Chlorine binding site 5 out of 6 in the Crystal Structure of Hsv-1 UL21 C-Terminal Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of Hsv-1 UL21 C-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl605 b:87.7 occ:1.00 NH2 A:ARG472 3.6 56.1 1.0 NH1 A:ARG399 3.9 65.6 1.0 CA A:GLY396 3.9 56.4 1.0 NH1 A:ARG472 4.2 50.1 1.0 CZ A:ARG472 4.4 52.0 1.0 N A:GLY396 4.5 55.4 1.0 CD A:ARG399 4.8 56.4 1.0 O A:ASP392 4.9 51.5 1.0 CD2 A:LEU340 5.0 59.2 1.0

Chlorine binding site 6 out of 6 in the Crystal Structure of Hsv-1 UL21 C-Terminal Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of Hsv-1 UL21 C-Terminal Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl606 b:95.2 occ:1.00 NH1 A:ARG470 3.0 0.4 1.0 NH2 A:ARG470 3.4 0.5 1.0 CZ A:ARG470 3.5 0.4 1.0 CG2 A:VAL465 4.1 60.7 1.0 CA A:VAL465 4.2 64.5 1.0 O A:SER464 4.3 67.3 1.0 N A:VAL465 4.5 66.8 1.0 C A:SER464 4.6 68.3 1.0 NE A:ARG470 4.6 0.7 1.0 CB A:VAL465 4.6 61.1 1.0 CG1 A:VAL465 4.9 61.1 1.0

C.M.Metrick, E.E.Heldwein. Novel Structure and Unexpected Rna-Binding Ability of the C-Terminal Domain of Herpes Simplex Virus 1 Tegument Protein UL21. J.Virol. V. 90 5759 2016.
ISSN: ESSN 1098-5514
PubMed: 27053559
DOI: 10.1128/JVI.00475-16