Chlorine in PDB 5ew4: Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+

The structure of Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+, PDB code: 5ew4 was solved by D.R.Tomchick, D.W.Dodd, K.T.Gagnon, D.R.Corey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.92 / 1.47
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.020, 47.615, 58.900, 90.00, 90.00, 90.00
R / Rfree (%)	21.6 / 23.9

The structure of Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+ also contains other interesting chemical elements:

Strontium	(Sr)	1 atom
Magnesium	(Mg)	2 atoms
Potassium	(K)	9 atoms

The binding sites of Chlorine atom in the Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+ (pdb code 5ew4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+, PDB code: 5ew4:

Chlorine binding site 1 out of 1 in the Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of C9ORF72 Antisense Ccccgg Repeat Rna Associated with Lou Gehrig'S Disease and Frontotemporal Dementia, Crystallized with SR2+ within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl111 b:20.6 occ:1.00 K B:K106 2.4 18.4 1.0 O B:HOH274 2.5 31.3 1.0 O B:HOH224 2.6 21.0 1.0 O6 B:G6 2.8 23.5 1.0 O B:HOH280 2.8 31.5 1.0 O B:HOH236 3.1 33.0 1.0 O6 B:G5 3.2 26.6 1.0 H42 A:C19 3.5 19.1 1.0 O A:HOH223 3.6 36.5 1.0 C6 B:G6 3.8 23.7 1.0 H41 B:C7 3.9 31.7 1.0 C6 B:G5 4.0 27.0 1.0 O B:HOH283 4.1 27.4 1.0 N7 B:G6 4.1 25.8 1.0 H41 A:C19 4.1 19.1 1.0 H42 A:C20 4.1 24.2 1.0 N4 A:C19 4.2 15.9 1.0 H42 B:C7 4.2 31.7 1.0 N4 B:C7 4.3 26.4 1.0 C5 B:G6 4.3 24.7 1.0 O B:HOH223 4.5 39.6 1.0 O6 A:G18 4.5 19.5 1.0 C5 B:G5 4.5 27.5 1.0 N7 B:G5 4.6 28.2 1.0 N4 A:C20 4.7 20.1 1.0 O B:HOH217 4.7 31.9 1.0 N1 B:G5 4.9 26.2 1.0 H41 A:C20 4.9 24.2 1.0 H1 B:G5 5.0 31.4 1.0

D.W.Dodd, D.R.Tomchick, D.R.Corey, K.T.Gagnon. Pathogenic C9ORF72 Antisense Repeat Rna Forms A Double Helix with Tandem C:C Mismatches. Biochemistry V. 55 1283 2016.
ISSN: ISSN 0006-2960
PubMed: 26878348
DOI: 10.1021/ACS.BIOCHEM.6B00136