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Atomistry » Chlorine » PDB 5f01-5f62 » 5f2s | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5f01-5f62 » 5f2s » |
Chlorine in PDB 5f2s: Crystal Structure of Human KDM4A in Complex with Compound 15Protein crystallography data
The structure of Crystal Structure of Human KDM4A in Complex with Compound 15, PDB code: 5f2s
was solved by
Y.-V.Le Bihan,
S.Dempster,
I.M.Westwood,
R.L.M.Van Montfort,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5f2s:
The structure of Crystal Structure of Human KDM4A in Complex with Compound 15 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human KDM4A in Complex with Compound 15
(pdb code 5f2s). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human KDM4A in Complex with Compound 15, PDB code: 5f2s: Chlorine binding site 1 out of 1 in 5f2sGo back to Chlorine Binding Sites List in 5f2s
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human KDM4A in Complex with Compound 15
Mono view Stereo pair view
Reference:
V.Bavetsias,
R.M.Lanigan,
G.F.Ruda,
B.Atrash,
M.G.Mclaughlin,
A.Tumber,
N.Y.Mok,
Y.V.Le Bihan,
S.Dempster,
K.J.Boxall,
F.Jeganathan,
S.B.Hatch,
P.Savitsky,
S.Velupillai,
T.Krojer,
K.S.England,
J.Sejberg,
C.Thai,
A.Donovan,
A.Pal,
G.Scozzafava,
J.M.Bennett,
A.Kawamura,
C.Johansson,
A.Szykowska,
C.Gileadi,
N.A.Burgess-Brown,
F.Von Delft,
U.Oppermann,
Z.Walters,
J.Shipley,
F.I.Raynaud,
S.M.Westaway,
R.K.Prinjha,
O.Fedorov,
R.Burke,
C.J.Schofield,
I.M.Westwood,
C.Bountra,
S.Muller,
R.L.Van Montfort,
P.E.Brennan,
J.Blagg.
8-Substituted Pyrido[3,4-D]Pyrimidin-4(3H)-One Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem. V. 59 1388 2016.
Page generated: Sat Dec 12 11:42:43 2020
ISSN: ISSN 0022-2623 PubMed: 26741168 DOI: 10.1021/ACS.JMEDCHEM.5B01635 |
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