Chlorine in PDB 5f3x: Crystal Structure of Harmonin NPDZ1 in Complex with ANKS4B Sam-Pbm

The structure of Crystal Structure of Harmonin NPDZ1 in Complex with ANKS4B Sam-Pbm, PDB code: 5f3x was solved by J.Li, Y.He, Q.Lu, M.Zhang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.51 / 2.65
Space group	P 32
Cell size a, b, c (Å), α, β, γ (°)	124.566, 124.566, 49.654, 90.00, 90.00, 120.00
R / Rfree (%)	22.7 / 26.4

The binding sites of Chlorine atom in the Crystal Structure of Harmonin NPDZ1 in Complex with ANKS4B Sam-Pbm (pdb code 5f3x). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Harmonin NPDZ1 in Complex with ANKS4B Sam-Pbm, PDB code: 5f3x:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Harmonin NPDZ1 in Complex with ANKS4B Sam-Pbm


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Harmonin NPDZ1 in Complex with ANKS4B Sam-Pbm within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:67.6 occ:1.00 N B:ALA351 3.0 67.8 1.0 NH2 A:ARG136 3.3 72.8 1.0 N A:SER141 3.3 58.9 1.0 OD1 B:ASP350 3.5 77.6 1.0 CA B:ASP350 3.5 79.5 1.0 CB B:ASP350 3.6 79.7 1.0 CA A:TYR140 3.7 61.5 1.0 C B:ASP350 3.8 74.5 1.0 CB B:ALA351 3.8 57.0 1.0 CG B:ASP350 3.9 79.4 1.0 CA B:ALA351 4.0 58.3 1.0 C A:TYR140 4.0 59.1 1.0 O A:GLY139 4.1 69.8 1.0 CD1 A:TYR140 4.1 56.7 1.0 CB A:SER141 4.2 58.5 1.0 CB A:TYR140 4.3 52.8 1.0 CA A:SER141 4.3 51.6 1.0 CZ A:ARG136 4.4 70.6 1.0 O B:ALA351 4.4 55.4 1.0 CG A:TYR140 4.7 54.8 1.0 C B:ALA351 4.7 55.7 1.0 N A:TYR140 4.7 61.0 1.0 NE A:ARG136 4.8 67.2 1.0 C A:GLY139 4.8 66.1 1.0 O A:SER141 4.8 55.4 1.0 N B:ASP350 4.9 84.4 1.0 CG2 B:VAL356 4.9 40.2 1.0 OD2 B:ASP350 5.0 80.2 1.0 O B:ASP350 5.0 75.0 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Harmonin NPDZ1 in Complex with ANKS4B Sam-Pbm


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Harmonin NPDZ1 in Complex with ANKS4B Sam-Pbm within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl201 b:77.0 occ:1.00 N D:ALA351 3.1 79.3 1.0 N C:SER141 3.2 60.4 1.0 CB D:ASP350 3.2 97.5 1.0 NH2 C:ARG136 3.5 67.8 1.0 CA C:TYR140 3.5 61.4 1.0 CA D:ASP350 3.7 98.8 1.0 C C:TYR140 3.8 61.5 1.0 CB D:ALA351 3.9 70.3 1.0 OD1 D:ASP350 3.9 92.6 1.0 C D:ASP350 3.9 88.7 1.0 O C:GLY139 4.0 68.7 1.0 CD1 C:TYR140 4.0 54.6 1.0 CG D:ASP350 4.1 96.2 1.0 CA D:ALA351 4.1 69.1 1.0 CB C:TYR140 4.1 51.4 1.0 CB C:SER141 4.1 51.8 1.0 CA C:SER141 4.2 50.6 1.0 O D:ALA351 4.4 63.0 1.0 CZ C:ARG136 4.5 66.4 1.0 CG C:TYR140 4.5 53.0 1.0 N C:TYR140 4.6 59.7 1.0 O C:SER141 4.6 47.9 1.0 NE C:ARG136 4.7 64.0 1.0 C C:GLY139 4.7 67.2 1.0 C D:ALA351 4.8 63.3 1.0 CG2 D:VAL356 4.9 41.1 1.0 C C:SER141 4.9 57.0 1.0

J.Li, Y.He, Q.Lu, M.Zhang. Mechanistic Basis of Organization of the Harmonin/USH1C-Mediated Brush Border Microvilli Tip-Link Complex Dev.Cell V. 36 179 2016.
ISSN: ISSN 1534-5807
PubMed: 26812017
DOI: 10.1016/J.DEVCEL.2015.12.020