Chlorine in PDB 5fbv: PI4KB in Complex with RAB11 and the MI364 Inhibitor

All present enzymatic activity of PI4KB in Complex with RAB11 and the MI364 Inhibitor:
2.7.1.67;

The structure of PI4KB in Complex with RAB11 and the MI364 Inhibitor, PDB code: 5fbv was solved by D.Chalupska, I.Mejdrova, R.Nencka, E.Boura, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.97 / 3.29
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	48.536, 102.782, 186.141, 90.00, 90.00, 90.00
R / Rfree (%)	23.7 / 28.1

The binding sites of Chlorine atom in the PI4KB in Complex with RAB11 and the MI364 Inhibitor (pdb code 5fbv). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the PI4KB in Complex with RAB11 and the MI364 Inhibitor, PDB code: 5fbv:

Chlorine binding site 1 out of 1 in the PI4KB in Complex with RAB11 and the MI364 Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of PI4KB in Complex with RAB11 and the MI364 Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl801 b:0.6 occ:1.00 CL A:5W3801 0.0 0.6 1.0 C25 A:5W3801 1.8 0.0 1.0 N24 A:5W3801 2.7 0.1 1.0 C26 A:5W3801 2.9 97.2 1.0 CD2 A:LEU374 3.7 91.8 1.0 CD1 A:LEU374 3.9 90.9 1.0 N22 A:5W3801 4.1 96.9 1.0 O1 A:5W3801 4.1 98.8 1.0 CG A:LEU374 4.1 91.5 1.0 C27 A:5W3801 4.2 91.2 1.0 CB A:LEU374 4.3 94.4 1.0 C11 A:5W3801 4.3 95.1 1.0 C23 A:5W3801 4.7 94.5 1.0 C7 A:5W3801 4.7 88.5 1.0 O9 A:5W3801 4.8 97.2 1.0 C12 A:5W3801 4.9 0.2 1.0

D.Chalupska, I.Mejdrova, R.Nencka, E.Boura. PI4KB in Complex with RAB11 and the MI364 Inhibitor To Be Published.