Chlorine in PDB 5fda: The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A

All present enzymatic activity of The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A:
1.5.1.3;

The structure of The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A, PDB code: 5fda was solved by C.Chang, N.Maltseva, Y.Kim, M.Makowska-Grzyska, R.Mulligan, L.Papazisi, W.F.Anderson, A.Joachimiak, Center For Structural Genomics Ofinfectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.96 / 1.55
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	60.265, 79.201, 64.321, 90.00, 90.00, 90.00
R / Rfree (%)	15.7 / 19.4

The binding sites of Chlorine atom in the The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A (pdb code 5fda). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A, PDB code: 5fda:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:10.1 occ:0.50 NZ A:LYS39 3.1 10.5 1.0 OD1 A:ASN35 3.4 12.2 1.0 CB A:ASN35 3.6 7.0 1.0 O A:HOH368 3.6 11.8 1.0 CE A:LYS39 3.8 9.8 1.0 CG A:ASN35 3.9 8.8 1.0 O A:ASN35 4.0 11.2 1.0 CA A:ASN35 4.4 7.0 1.0 OE1 A:GLU90 4.4 24.3 1.0 C A:ASN35 4.4 8.4 1.0 CL A:CL202 4.5 13.1 0.5 CE1 A:PHE32 4.8 10.4 1.0

Chlorine binding site 2 out of 3 in the The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:13.1 occ:0.50 O A:HOH417 3.1 16.6 1.0 ND2 A:ASN38 3.3 13.4 1.0 NZ A:LYS39 3.4 10.5 1.0 CE A:LYS39 3.5 9.8 1.0 OD1 A:ASN38 3.9 14.2 1.0 CG A:ASN38 4.0 11.6 1.0 CD A:LYS39 4.4 10.6 1.0 OE1 A:GLU90 4.4 24.3 1.0 CL A:CL201 4.5 10.1 0.5 CB A:GLU90 4.6 15.3 1.0 O A:HOH459 4.8 31.4 1.0 O A:HOH378 5.0 19.4 1.0

Chlorine binding site 3 out of 3 in the The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The High Resolution Structure of Apo Form Dihydrofolate Reductase From Yersinia Pestis at 1.55 A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl203 b:22.6 occ:0.50 O A:HOH424 3.1 29.7 1.0 O A:HOH304 3.1 28.0 0.5 N A:SER149 3.4 11.7 1.0 OG A:SER149 3.5 25.2 1.0 CE1 A:HIS24 3.8 18.1 1.0 CA A:ASN148 3.9 11.9 1.0 O A:ALA147 4.0 14.1 1.0 C A:ASN148 4.1 10.7 1.0 CB A:SER149 4.3 20.5 1.0 ND1 A:HIS24 4.4 18.4 1.0 CA A:SER149 4.4 14.7 1.0 O A:HOH360 4.4 22.5 1.0 N A:ASN148 4.6 10.1 1.0 C A:ALA147 4.6 11.7 1.0 NE2 A:HIS24 4.7 16.1 1.0 CB A:ASN148 4.9 13.4 1.0

C.Chang, N.Maltseva, Y.Kim, M.Makowska-Grzyska, R.Mulligan, L.Papazisi, W.F.Anderson, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Structure of Dihydrofolate Reductase From Yersinia Pestis Complex with To Be Published.