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Atomistry » Chlorine » PDB 5fdf-5fjg » 5fdl » |
Chlorine in PDB 5fdl: Crystal Structure of K103N/Y181C Mutant Hiv-1 Reverse Transcriptase (Rt) in Complex with IDX899Enzymatic activity of Crystal Structure of K103N/Y181C Mutant Hiv-1 Reverse Transcriptase (Rt) in Complex with IDX899
All present enzymatic activity of Crystal Structure of K103N/Y181C Mutant Hiv-1 Reverse Transcriptase (Rt) in Complex with IDX899:
2.7.7.49; Protein crystallography data
The structure of Crystal Structure of K103N/Y181C Mutant Hiv-1 Reverse Transcriptase (Rt) in Complex with IDX899, PDB code: 5fdl
was solved by
C.B.Dousson,
F.-R.Alexandre,
T.Convard,
M.Fisher,
M.B.A.C.Lamers,
P.M.Leonard,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of K103N/Y181C Mutant Hiv-1 Reverse Transcriptase (Rt) in Complex with IDX899
(pdb code 5fdl). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of K103N/Y181C Mutant Hiv-1 Reverse Transcriptase (Rt) in Complex with IDX899, PDB code: 5fdl: Chlorine binding site 1 out of 1 in 5fdlGo back to Chlorine Binding Sites List in 5fdl
Chlorine binding site 1 out
of 1 in the Crystal Structure of K103N/Y181C Mutant Hiv-1 Reverse Transcriptase (Rt) in Complex with IDX899
Mono view Stereo pair view
Reference:
C.Dousson,
F.R.Alexandre,
A.Amador,
S.Bonaric,
S.Bot,
C.Caillet,
T.Convard,
D.Da Costa,
M.P.Lioure,
A.Roland,
E.Rosinovsky,
S.Maldonado,
C.Parsy,
C.Trochet,
R.Storer,
A.Stewart,
J.Wang,
B.A.Mayes,
C.Musiu,
B.Poddesu,
L.Vargiu,
M.Liuzzi,
A.Moussa,
J.Jakubik,
L.Hubbard,
M.Seifer,
D.Standring.
Discovery of the Aryl-Phospho-Indole IDX899, A Highly Potent Anti-Hiv Non-Nucleoside Reverse Transcriptase Inhibitor. J.Med.Chem. V. 59 1891 2016.
Page generated: Sat Dec 12 11:43:43 2020
ISSN: ISSN 0022-2623 PubMed: 26804933 DOI: 10.1021/ACS.JMEDCHEM.5B01430 |
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