Chlorine in PDB 5fxt: Crystal Structure of Helicobacter Pylori Beta Clamp in Complex with Carprofen

All present enzymatic activity of Crystal Structure of Helicobacter Pylori Beta Clamp in Complex with Carprofen:
2.7.7.7;

The structure of Crystal Structure of Helicobacter Pylori Beta Clamp in Complex with Carprofen, PDB code: 5fxt was solved by P.Pandey, S.Gourinath, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	74.76 / 1.97
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	89.921, 66.445, 82.867, 90.00, 115.56, 90.00
R / Rfree (%)	20.7 / 26

The binding sites of Chlorine atom in the Crystal Structure of Helicobacter Pylori Beta Clamp in Complex with Carprofen (pdb code 5fxt). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Helicobacter Pylori Beta Clamp in Complex with Carprofen, PDB code: 5fxt:

Chlorine binding site 1 out of 1 in the Crystal Structure of Helicobacter Pylori Beta Clamp in Complex with Carprofen


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Helicobacter Pylori Beta Clamp in Complex with Carprofen within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1376 b:48.3 occ:0.80 CL A:0LA1376 0.0 48.3 0.8 C3 A:0LA1376 1.8 48.7 0.8 C2 A:0LA1376 2.7 50.6 0.8 C4 A:0LA1376 2.8 49.3 0.8 O A:LEU369 3.2 44.6 1.0 O A:LYS177 3.5 49.6 1.0 CA A:ARG178 3.5 46.8 1.0 C A:LEU369 3.5 40.4 1.0 N A:LEU179 3.8 44.4 1.0 C A:LYS177 3.8 54.4 1.0 C A:ARG178 3.8 44.3 1.0 CD2 A:LEU369 3.8 46.6 1.0 N A:MET370 3.8 41.1 1.0 CA A:MET370 3.8 45.3 1.0 N A:ARG178 3.9 50.5 1.0 CG A:LEU369 4.0 45.7 1.0 C4A A:0LA1376 4.0 50.0 0.8 N A:MET371 4.1 48.6 1.0 C1 A:0LA1376 4.1 50.4 0.8 CB A:LEU369 4.1 44.1 1.0 C A:MET370 4.1 46.8 1.0 CB A:LEU179 4.2 46.5 1.0 CG A:MET371 4.2 58.1 1.0 CA A:LEU369 4.5 42.6 1.0 O A:ARG178 4.6 46.5 1.0 C9A A:0LA1376 4.6 51.2 0.8 CA A:LEU179 4.6 46.3 1.0 O A:THR176 4.7 55.6 1.0 CA A:LYS177 4.8 57.5 1.0 CB A:ARG178 4.8 44.5 1.0 O A:MET370 5.0 44.7 1.0 CA A:MET371 5.0 52.4 1.0 CB A:MET371 5.0 54.5 1.0

P.Pandey, V.Verma, S.K.Dhar, S.Gourinath. Screening of E. Coli Beta-Clamp Inhibitors Revealed That Few Inhibit Helicobacter Pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel) V. 7 2018.
ISSN: ESSN 2079-6382
PubMed: 29324718
DOI: 10.3390/ANTIBIOTICS7010005