Atomistry » Chlorine » PDB 5gqq-5h3g » 5gtz
Atomistry »
  Chlorine »
    PDB 5gqq-5h3g »
      5gtz »

Chlorine in PDB 5gtz: Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39

Enzymatic activity of Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39

All present enzymatic activity of Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39:
2.7.10.1;

Protein crystallography data

The structure of Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39, PDB code: 5gtz was solved by X.E.Yan, C.H.Yun, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.20 / 3.00
Space group I 2 3
Cell size a, b, c (Å), α, β, γ (°) 146.177, 146.177, 146.177, 90.00, 90.00, 90.00
R / Rfree (%) 18.9 / 23

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39 (pdb code 5gtz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39, PDB code: 5gtz:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 5gtz

Go back to Chlorine Binding Sites List in 5gtz
Chlorine binding site 1 out of 6 in the Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1101

b:49.3
occ:1.00
 CL5 A:81C1101 0.0 49.3 1.0
C5 A:81C1101 1.8 49.6 1.0
C6 A:81C1101 2.7 46.3 1.0
C4 A:81C1101 2.8 47.5 1.0
NBE A:81C1101 2.9 49.5 1.0
CBR A:81C1101 3.4 74.0 1.0
CB A:ALA743 3.8 38.7 1.0
SD A:MET790 3.8 60.0 1.0
CE A:MET790 3.9 67.3 1.0
CAC A:81C1101 4.0 69.8 1.0
N3 A:81C1101 4.0 43.9 1.0
N1 A:81C1101 4.0 47.3 1.0
CG A:MET790 4.1 47.5 1.0
CAD A:81C1101 4.2 65.5 1.0
CBK A:81C1101 4.2 54.9 1.0
CB A:MET790 4.3 49.5 1.0
CD1 A:LEU844 4.5 47.5 1.0
C2 A:81C1101 4.5 48.0 1.0
SBV A:81C1101 4.7 66.0 1.0
O A:GLN791 4.8 43.0 1.0
CG1 A:VAL726 4.9 49.3 1.0
CBQ A:81C1101 4.9 57.7 1.0

Chlorine binding site 2 out of 6 in 5gtz

Go back to Chlorine Binding Sites List in 5gtz
Chlorine binding site 2 out of 6 in the Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1106

b:79.6
occ:1.00
 CG A:ARG776 3.3 52.4 0.5
CG A:ARG776 3.4 52.4 0.5
NE A:ARG776 3.5 51.9 0.5
NH1 A:ARG776 3.6 58.0 0.5
CD2 A:LEU778 3.8 44.8 1.0
O A:TYR1016 3.8 50.5 1.0
CZ A:ARG776 3.8 57.8 0.5
O A:ALA1013 3.9 57.8 1.0
CD A:ARG776 4.0 51.3 0.5
NH2 A:ARG776 4.1 54.3 0.5
CZ A:ARG776 4.1 51.6 0.5
CD A:ARG776 4.2 51.0 0.5
CB A:ARG776 4.3 52.5 0.5
NE A:ARG776 4.4 53.2 0.5
CB A:ARG776 4.5 51.5 0.5
O A:HOH1239 4.5 63.6 1.0
NH1 A:ARG776 4.5 54.1 0.5
C A:ALA1013 4.8 53.4 1.0
CD1 A:LEU1017 4.9 53.0 1.0
NH2 A:ARG776 5.0 41.7 0.5
CB A:ALA1013 5.0 52.0 1.0
CG A:LEU778 5.0 43.0 1.0

Chlorine binding site 3 out of 6 in 5gtz

Go back to Chlorine Binding Sites List in 5gtz
Chlorine binding site 3 out of 6 in the Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1107

b:84.4
occ:1.00
 N A:GLY721 3.9 94.3 1.0
CG2 A:VAL726 4.0 64.9 1.0
CA A:GLY721 4.1 98.0 1.0
O A:GLY724 4.2 99.2 1.0
OAI A:81C1101 4.3 71.6 1.0
C A:GLY724 4.5 96.9 1.0
O A:GLY719 4.5 65.3 1.0
C A:SER720 4.6 90.6 1.0
CAO A:81C1101 4.9 51.1 1.0
C A:GLY719 4.9 71.8 1.0
CA A:GLY724 4.9 0.9 1.0
N A:THR725 5.0 92.0 1.0

Chlorine binding site 4 out of 6 in 5gtz

Go back to Chlorine Binding Sites List in 5gtz
Chlorine binding site 4 out of 6 in the Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1108

b:91.4
occ:1.00
 N A:GLY735 2.5 78.2 1.0
CA A:GLU734 2.9 88.5 1.0
C A:GLU734 3.2 85.0 1.0
O A:PRO733 3.3 74.3 1.0
CA A:GLY735 3.7 78.2 1.0
CG A:GLU734 3.7 80.5 1.0
CB A:GLU734 3.8 84.0 1.0
N A:GLU734 3.8 81.2 1.0
C A:PRO733 3.9 77.8 1.0
O A:HOH1227 4.0 71.6 1.0
O A:GLU734 4.4 82.2 1.0
N A:GLU736 4.6 81.9 1.0
C A:GLY735 4.6 82.3 1.0
O A:ILE732 4.7 65.3 1.0
CD A:GLU734 4.8 85.8 0.0
CG2 A:ILE732 4.8 63.5 1.0
OE1 A:GLU734 5.0 92.4 1.0

Chlorine binding site 5 out of 6 in 5gtz

Go back to Chlorine Binding Sites List in 5gtz
Chlorine binding site 5 out of 6 in the Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1109

b:77.7
occ:1.00
 NZ A:LYS713 3.2 88.8 1.0
O A:THR710 3.6 58.3 1.0
CD1 A:ILE732 3.9 66.2 1.0
CE A:LYS713 4.3 94.8 1.0
O A:GLU711 4.5 53.4 1.0
C A:GLU711 4.6 53.0 1.0
N A:PHE712 4.6 50.6 1.0
CB A:LYS713 4.7 68.3 1.0
C A:PHE712 4.7 59.3 1.0
N A:LYS713 4.7 62.0 1.0
CA A:PHE712 4.7 53.9 1.0
C A:THR710 4.8 57.1 1.0

Chlorine binding site 6 out of 6 in 5gtz

Go back to Chlorine Binding Sites List in 5gtz
Chlorine binding site 6 out of 6 in the Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1110

b:81.8
occ:1.00
 O A:HOH1246 4.0 46.9 1.0

Reference:

X.E.Yan, C.H.Yun. Crystal Structure of Egfr 696-1022 T790M in Complex with Jts-1-39 To Be Published.
Page generated: Fri Jul 26 08:34:05 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy