Chlorine in PDB 5h8e: Crystal Structure of CK2 with Compound 7H

All present enzymatic activity of Crystal Structure of CK2 with Compound 7H:
2.7.11.1;

The structure of Crystal Structure of CK2 with Compound 7H, PDB code: 5h8e was solved by A.D.Ferguson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.60 / 2.15
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	126.920, 126.920, 124.570, 90.00, 90.00, 90.00
R / Rfree (%)	16.5 / 19.6

The binding sites of Chlorine atom in the Crystal Structure of CK2 with Compound 7H (pdb code 5h8e). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of CK2 with Compound 7H, PDB code: 5h8e:

Chlorine binding site 1 out of 1 in the Crystal Structure of CK2 with Compound 7H


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of CK2 with Compound 7H within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl407 b:76.9 occ:1.00 O B:HOH657 2.9 38.0 1.0 O B:HOH716 2.9 36.9 1.0 CD B:LYS74 4.1 57.9 1.0 CA B:LYS74 4.4 35.8 1.0 N B:LYS75 4.5 31.5 1.0 CB B:LYS74 4.6 38.1 1.0 CG B:LYS74 4.6 50.0 1.0 C B:LYS74 5.0 35.3 1.0

J.E.Dowling, M.Alimzhanov, L.Bao, C.Chuaqui, C.R.Denz, E.Jenkins, N.A.Larsen, P.D.Lyne, T.Pontz, Q.Ye, G.A.Holdgate, L.Snow, N.O'connell, A.D.Ferguson. Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo. Acs Med.Chem.Lett. V. 7 300 2016.
ISSN: ISSN 1948-5875
PubMed: 26985319
DOI: 10.1021/ACSMEDCHEMLETT.5B00452