Chlorine in PDB 5hgj: Structure of Integrin ALPHA1BETA1 and ALPHA2BETA1 I-Domains Explain Differential Calcium-Mediated Ligand Recognition

The structure of Structure of Integrin ALPHA1BETA1 and ALPHA2BETA1 I-Domains Explain Differential Calcium-Mediated Ligand Recognition, PDB code: 5hgj was solved by K.L.Brown, S.Banerjee, A.Feigley, H.Abe, T.Blackwell, R.Zent, A.Pozzi, B.H.Hudson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.98 / 1.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	37.369, 95.950, 53.078, 90.00, 104.00, 90.00
R / Rfree (%)	17.8 / 20.5

The structure of Structure of Integrin ALPHA1BETA1 and ALPHA2BETA1 I-Domains Explain Differential Calcium-Mediated Ligand Recognition also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Chlorine atom in the Structure of Integrin ALPHA1BETA1 and ALPHA2BETA1 I-Domains Explain Differential Calcium-Mediated Ligand Recognition (pdb code 5hgj). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Integrin ALPHA1BETA1 and ALPHA2BETA1 I-Domains Explain Differential Calcium-Mediated Ligand Recognition, PDB code: 5hgj:

Chlorine binding site 1 out of 1 in the Structure of Integrin ALPHA1BETA1 and ALPHA2BETA1 I-Domains Explain Differential Calcium-Mediated Ligand Recognition


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Integrin ALPHA1BETA1 and ALPHA2BETA1 I-Domains Explain Differential Calcium-Mediated Ligand Recognition within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl602 b:47.4 occ:1.00 O A:HOH810 3.3 32.8 1.0 O A:HOH843 3.4 34.2 1.0 O A:HOH784 4.6 27.2 1.0 O A:GLU126 4.8 15.8 1.0 O A:HOH918 4.9 21.2 1.0 O A:ALA127 4.9 18.4 1.0

K.L.Brown, S.Banerjee, A.Feigley, H.Abe, T.S.Blackwell, A.Pozzi, B.G.Hudson, R.Zent. Salt-Bridge Modulates Differential Calcium-Mediated Ligand Binding to Integrin Alpha 1- and Alpha 2-I Domains. Sci Rep V. 8 2916 2018.
ISSN: ESSN 2045-2322
PubMed: 29440721
DOI: 10.1038/S41598-018-21231-1