Chlorine in PDB 5i6u: The Crystal Structure of PI3KDELTA with Compound 32

All present enzymatic activity of The Crystal Structure of PI3KDELTA with Compound 32:
2.7.1.153;

The structure of The Crystal Structure of PI3KDELTA with Compound 32, PDB code: 5i6u was solved by J.R.Somoza, A.G.Villasenor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.66 / 2.84
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	142.836, 64.926, 117.058, 90.00, 103.17, 90.00
R / Rfree (%)	21.2 / 30.7

The binding sites of Chlorine atom in the The Crystal Structure of PI3KDELTA with Compound 32 (pdb code 5i6u). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Crystal Structure of PI3KDELTA with Compound 32, PDB code: 5i6u:

Chlorine binding site 1 out of 1 in the The Crystal Structure of PI3KDELTA with Compound 32


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of PI3KDELTA with Compound 32 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1101 b:73.7 occ:1.00 CL1 A:68R1101 0.0 73.7 1.0 C06 A:68R1101 1.7 36.5 1.0 C01 A:68R1101 2.6 31.5 1.0 C05 A:68R1101 2.8 37.3 1.0 O11 A:68R1101 3.0 35.1 1.0 CG2 A:THR750 3.3 26.4 1.0 C10 A:68R1101 3.3 36.5 1.0 N A:MET752 3.4 32.9 1.0 C A:PHE751 3.5 32.5 1.0 O A:PHE751 3.8 33.5 1.0 CA A:MET752 3.8 37.3 1.0 CB A:TRP760 3.8 27.1 1.0 C02 A:68R1101 3.9 34.2 1.0 CA A:PHE751 3.9 30.7 1.0 CB A:MET752 4.0 38.0 1.0 N A:PHE751 4.0 29.2 1.0 C04 A:68R1101 4.1 37.3 1.0 CG A:TRP760 4.3 29.3 1.0 CE3 A:TRP760 4.3 26.9 1.0 OG1 A:THR750 4.3 35.9 1.0 CD2 A:TRP760 4.4 29.9 1.0 CB A:THR750 4.4 32.0 1.0 C03 A:68R1101 4.5 43.4 1.0 C A:THR750 4.5 25.6 1.0 N09 A:68R1101 4.8 34.0 1.0 O A:PRO758 4.9 31.8 1.0 O A:THR750 4.9 24.6 1.0

J.R.Somoza, A.G.Villasenor. The Crystal Structure of PI3KDELTA with Compound 32 To Be Published.