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Atomistry » Chlorine » PDB 5i1c-5ib5 » 5i7o | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5i1c-5ib5 » 5i7o » |
Chlorine in PDB 5i7o: Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid]Enzymatic activity of Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid]
All present enzymatic activity of Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid]:
2.5.1.113; Protein crystallography data
The structure of Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid], PDB code: 5i7o
was solved by
R.Schnell,
S.Maric,
G.Schneider,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid]
(pdb code 5i7o). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid], PDB code: 5i7o: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 5i7oGo back to Chlorine Binding Sites List in 5i7o
Chlorine binding site 1 out
of 4 in the Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid]
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 5i7oGo back to Chlorine Binding Sites List in 5i7o
Chlorine binding site 2 out
of 4 in the Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid]
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 5i7oGo back to Chlorine Binding Sites List in 5i7o
Chlorine binding site 3 out
of 4 in the Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid]
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 5i7oGo back to Chlorine Binding Sites List in 5i7o
Chlorine binding site 4 out
of 4 in the Mycobacterium Tuberculosis Cysm in Complex with the Urea-Scaffold Inhibitor 7 [3-(3-(4-Chlorophenyl)Ureido)Benzoic Acid]
Mono view Stereo pair view
Reference:
K.Brunner,
S.Maric,
R.S.Reshma,
H.Almqvist,
B.Seashore-Ludlow,
A.L.Gustavsson,
O.Poyraz,
P.Yogeeswari,
T.Lundback,
M.Vallin,
D.Sriram,
R.Schnell,
G.Schneider.
Inhibitors of the Cysteine Synthase Cysm with Antibacterial Potency Against Dormant Mycobacterium Tuberculosis. J.Med.Chem. V. 59 6848 2016.
Page generated: Sat Dec 12 11:50:09 2020
ISSN: ISSN 0022-2623 PubMed: 27379713 DOI: 10.1021/ACS.JMEDCHEM.6B00674 |
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