Chlorine in PDB 5inn: Mouse TDP2 D358N Protein, Apo State with Increased Disorder Amongst Variable Dna-Binding Grasp Conformations

The structure of Mouse TDP2 D358N Protein, Apo State with Increased Disorder Amongst Variable Dna-Binding Grasp Conformations, PDB code: 5inn was solved by M.J.Schellenberg, C.D.Appel, R.S.Williams, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.39 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	95.440, 114.880, 115.450, 90.00, 90.00, 90.00
R / Rfree (%)	21.3 / 25.6

The binding sites of Chlorine atom in the Mouse TDP2 D358N Protein, Apo State with Increased Disorder Amongst Variable Dna-Binding Grasp Conformations (pdb code 5inn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Mouse TDP2 D358N Protein, Apo State with Increased Disorder Amongst Variable Dna-Binding Grasp Conformations, PDB code: 5inn:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Mouse TDP2 D358N Protein, Apo State with Increased Disorder Amongst Variable Dna-Binding Grasp Conformations


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Mouse TDP2 D358N Protein, Apo State with Increased Disorder Amongst Variable Dna-Binding Grasp Conformations within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl401 b:31.3 occ:1.00 NH2 B:ARG327 3.3 58.0 1.0 NH1 B:ARG327 3.6 52.5 1.0 CZ B:ARG327 3.9 53.1 1.0 NH2 B:ARG324 4.2 44.0 1.0 O B:ASP277 4.3 92.2 1.0 O B:HOH535 4.8 45.1 1.0 CG2 B:VAL280 4.8 42.2 1.0

Chlorine binding site 2 out of 2 in the Mouse TDP2 D358N Protein, Apo State with Increased Disorder Amongst Variable Dna-Binding Grasp Conformations


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Mouse TDP2 D358N Protein, Apo State with Increased Disorder Amongst Variable Dna-Binding Grasp Conformations within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl402 b:45.6 occ:0.90 N C:GLY346 3.2 46.0 1.0 OH C:TYR153 3.3 38.6 1.0 N C:LEU347 3.4 82.5 1.0 CA C:VAL345 3.9 48.2 1.0 CA C:GLY346 4.0 49.3 1.0 C C:VAL345 4.0 49.4 1.0 C C:GLY346 4.2 51.9 1.0 CZ C:TYR153 4.3 36.4 1.0 CB C:LEU347 4.3 77.4 1.0 CA C:LEU347 4.3 79.3 1.0 N C:GLU348 4.4 0.4 1.0 CE2 C:TYR153 4.4 34.7 1.0 CG C:GLU348 4.6 0.5 1.0 O C:LEU344 4.6 44.1 1.0 CB C:VAL345 4.7 47.4 1.0 C C:LEU347 4.7 77.6 1.0 CD1 C:LEU347 4.9 74.4 1.0 N C:VAL345 5.0 39.7 1.0

M.J.Schellenberg, L.Perera, C.N.Strom, C.A.Waters, B.Monian, C.D.Appel, C.K.Vilas, J.G.Williams, D.A.Ramsden, R.S.Williams. Reversal of Dna Damage Induced Topoisomerase 2 Dna-Protein Crosslinks By TDP2. Nucleic Acids Res. V. 44 3829 2016.
ISSN: ESSN 1362-4962
PubMed: 27060144
DOI: 10.1093/NAR/GKW228