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Atomistry » Chlorine » PDB 5jen-5jkc » 5jhb | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5jen-5jkc » 5jhb » |
Chlorine in PDB 5jhb: Structure of Phosphoinositide 3-Kinase Gamma (PI3K) Bound to the Potent Inhibitor PIKIN3Enzymatic activity of Structure of Phosphoinositide 3-Kinase Gamma (PI3K) Bound to the Potent Inhibitor PIKIN3
All present enzymatic activity of Structure of Phosphoinositide 3-Kinase Gamma (PI3K) Bound to the Potent Inhibitor PIKIN3:
2.7.1.153; 2.7.11.1; Protein crystallography data
The structure of Structure of Phosphoinositide 3-Kinase Gamma (PI3K) Bound to the Potent Inhibitor PIKIN3, PDB code: 5jhb
was solved by
J.E.Burke,
A.J.Inglis,
R.L.Williams,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5jhb:
The structure of Structure of Phosphoinositide 3-Kinase Gamma (PI3K) Bound to the Potent Inhibitor PIKIN3 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Phosphoinositide 3-Kinase Gamma (PI3K) Bound to the Potent Inhibitor PIKIN3
(pdb code 5jhb). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Phosphoinositide 3-Kinase Gamma (PI3K) Bound to the Potent Inhibitor PIKIN3, PDB code: 5jhb: Chlorine binding site 1 out of 1 in 5jhbGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Structure of Phosphoinositide 3-Kinase Gamma (PI3K) Bound to the Potent Inhibitor PIKIN3
![]() Mono view ![]() Stereo pair view
Reference:
T.Bohnacker,
A.E.Prota,
F.Beaufils,
J.E.Burke,
A.Melone,
A.J.Inglis,
D.Rageot,
A.M.Sele,
V.Cmiljanovic,
N.Cmiljanovic,
K.Bargsten,
A.Aher,
A.Akhmanova,
J.F.Diaz,
D.Fabbro,
M.Zvelebil,
R.L.Williams,
M.O.Steinmetz,
M.P.Wymann.
Deconvolution of Buparlisib'S Mechanism of Action Defines Specific PI3K and Tubulin Inhibitors For Therapeutic Intervention. Nat Commun V. 8 14683 2017.
Page generated: Fri Jul 26 10:04:24 2024
ISSN: ESSN 2041-1723 PubMed: 28276440 DOI: 10.1038/NCOMMS14683 |
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