Chlorine in PDB 5jiz: Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp

All present enzymatic activity of Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp:
2.7.11.12;

The structure of Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp, PDB code: 5jiz was solved by J.C.Campbell, C.W.Kim, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.85 / 1.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	42.200, 50.210, 65.500, 90.00, 90.00, 90.00
R / Rfree (%)	18 / 19.8

The structure of Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Chlorine atom in the Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp (pdb code 5jiz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp, PDB code: 5jiz:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:17.8 occ:1.00 CL1 A:6FW501 0.0 17.8 1.0 C22 A:6FW501 1.7 10.0 1.0 C23 A:6FW501 2.7 20.0 1.0 C21 A:6FW501 2.7 11.0 1.0 HE1 A:TYR354 2.8 11.3 1.0 H231 A:6FW501 2.8 24.0 1.0 H211 A:6FW501 2.9 13.2 1.0 HB3 A:TYR404 3.2 15.3 1.0 HD22 A:LEU401 3.3 18.1 1.0 HH A:TYR354 3.3 18.2 1.0 HD2 A:TYR404 3.3 30.1 1.0 CD2 A:TYR404 3.3 25.1 1.0 HG3 A:GLU357 3.4 8.0 1.0 CD A:GLU357 3.6 7.9 1.0 CG A:TYR404 3.6 18.2 1.0 CE1 A:TYR354 3.6 9.4 1.0 HD11 A:LEU408 3.7 15.5 1.0 HD23 A:LEU401 3.7 18.1 1.0 OE2 A:GLU357 3.8 10.3 1.0 CE2 A:TYR404 3.9 29.1 1.0 CD2 A:LEU401 3.9 15.1 1.0 OE1 A:GLU357 3.9 7.3 1.0 CB A:TYR404 3.9 12.8 1.0 CG A:GLU357 3.9 6.7 1.0 C24 A:6FW501 4.0 15.5 1.0 C20 A:6FW501 4.0 9.5 1.0 OH A:TYR354 4.0 15.2 1.0 HG2 A:GLU357 4.1 8.0 1.0 HE2 A:TYR404 4.1 34.9 1.0 HD21 A:LEU401 4.2 18.1 1.0 HG23 A:VAL405 4.3 12.5 1.0 CD1 A:TYR404 4.3 13.8 1.0 CZ A:TYR354 4.3 14.8 1.0 HB2 A:TYR404 4.3 15.3 1.0 HA A:LEU401 4.5 11.1 1.0 HD1 A:TYR354 4.5 9.6 1.0 CZ A:TYR404 4.5 33.3 1.0 C19 A:6FW501 4.5 10.6 1.0 CD1 A:TYR354 4.6 8.0 1.0 CD1 A:LEU408 4.6 12.9 1.0 CE1 A:TYR404 4.7 26.0 1.0 H241 A:6FW501 4.8 18.6 1.0 H201 A:6FW501 4.8 11.4 1.0 HD1 A:TYR404 4.8 16.5 1.0 HG22 A:VAL405 4.8 12.5 1.0 HG A:LEU408 4.9 10.4 1.0 HB3 A:LEU401 4.9 15.8 1.0

Chlorine binding site 2 out of 2 in the Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl502 b:27.7 occ:1.00 CL1 A:6FW502 0.0 27.7 1.0 C22 A:6FW502 1.7 20.3 1.0 C21 A:6FW502 2.7 17.5 1.0 C23 A:6FW502 2.7 19.8 1.0 C24 A:6FW502 4.0 23.3 1.0 C20 A:6FW502 4.0 22.8 1.0 HB2 A:ALA406 4.4 12.8 1.0 C19 A:6FW502 4.5 30.5 1.0 HB3 A:GLU402 4.7 15.2 1.0

J.C.Campbell, C.W.Kim. Pkg II'S Carboxyl Terminal Cyclic Nucleotide Binding Domain (Cnb-B) in A Complex with 8-Pcpt-Cgmp To Be Published.