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Atomistry » Chlorine » PDB 5jsr-5jzk » 5juz » |
Chlorine in PDB 5juz: Crystal Structure of Human Fpps in Complex with An Allosteric Inhibitor Cl-06-057Enzymatic activity of Crystal Structure of Human Fpps in Complex with An Allosteric Inhibitor Cl-06-057
All present enzymatic activity of Crystal Structure of Human Fpps in Complex with An Allosteric Inhibitor Cl-06-057:
2.5.1.1; 2.5.1.10; Protein crystallography data
The structure of Crystal Structure of Human Fpps in Complex with An Allosteric Inhibitor Cl-06-057, PDB code: 5juz
was solved by
J.Park,
A.Magder,
C.Y.Leung,
Y.S.Tsantrizos,
A.M.Berghuis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Fpps in Complex with An Allosteric Inhibitor Cl-06-057
(pdb code 5juz). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Fpps in Complex with An Allosteric Inhibitor Cl-06-057, PDB code: 5juz: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 5juzGo back to Chlorine Binding Sites List in 5juz
Chlorine binding site 1 out
of 2 in the Crystal Structure of Human Fpps in Complex with An Allosteric Inhibitor Cl-06-057
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 5juzGo back to Chlorine Binding Sites List in 5juz
Chlorine binding site 2 out
of 2 in the Crystal Structure of Human Fpps in Complex with An Allosteric Inhibitor Cl-06-057
Mono view Stereo pair view
Reference:
J.Park,
C.Y.Leung,
A.N.Matralis,
C.M.Lacbay,
M.Tsakos,
G.Fernandez De Troconiz,
A.M.Berghuis,
Y.S.Tsantrizos.
Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (Thp-Mp) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. J. Med. Chem. V. 60 2119 2017.
Page generated: Sat Dec 12 11:54:26 2020
ISSN: ISSN 1520-4804 PubMed: 28208018 DOI: 10.1021/ACS.JMEDCHEM.6B01888 |
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