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Atomistry » Chlorine » PDB 5k9c-5kez » 5k9d | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5k9c-5kez » 5k9d » |
Chlorine in PDB 5k9d: Crystal Structure of Human Dihydroorotate Dehydrogenase at 1.7 A ResolutionEnzymatic activity of Crystal Structure of Human Dihydroorotate Dehydrogenase at 1.7 A Resolution
All present enzymatic activity of Crystal Structure of Human Dihydroorotate Dehydrogenase at 1.7 A Resolution:
1.3.5.2; Protein crystallography data
The structure of Crystal Structure of Human Dihydroorotate Dehydrogenase at 1.7 A Resolution, PDB code: 5k9d
was solved by
T.A.Lewis,
D.B.Sykes,
J.M.Law,
B.Munoz,
D.T.Scadden,
J.K.Rustiguel,
M.C.Nonato,
S.L.Schreiber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Dihydroorotate Dehydrogenase at 1.7 A Resolution
(pdb code 5k9d). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Human Dihydroorotate Dehydrogenase at 1.7 A Resolution, PDB code: 5k9d: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 5k9dGo back to Chlorine Binding Sites List in 5k9d
Chlorine binding site 1 out
of 3 in the Crystal Structure of Human Dihydroorotate Dehydrogenase at 1.7 A Resolution
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 5k9dGo back to Chlorine Binding Sites List in 5k9d
Chlorine binding site 2 out
of 3 in the Crystal Structure of Human Dihydroorotate Dehydrogenase at 1.7 A Resolution
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 5k9dGo back to Chlorine Binding Sites List in 5k9d
Chlorine binding site 3 out
of 3 in the Crystal Structure of Human Dihydroorotate Dehydrogenase at 1.7 A Resolution
Mono view Stereo pair view
Reference:
T.A.Lewis,
D.B.Sykes,
J.M.Law,
B.Munoz,
J.K.Rustiguel,
M.C.Nonato,
D.T.Scadden,
S.L.Schreiber.
Development of ML390: A Human Dhodh Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. Acs Med Chem Lett V. 7 1112 2016.
Page generated: Sat Dec 12 11:55:49 2020
ISSN: ISSN 1948-5875 PubMed: 27994748 DOI: 10.1021/ACSMEDCHEMLETT.6B00316 |
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