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Atomistry » Chlorine » PDB 5kga-5kor » 5kh3 » |
Chlorine in PDB 5kh3: Crystal Structure of Fragment (3-(5-Chloro-1,3-Benzothiazol-2-Yl) Propanoic Acid) Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger DomainEnzymatic activity of Crystal Structure of Fragment (3-(5-Chloro-1,3-Benzothiazol-2-Yl) Propanoic Acid) Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain
All present enzymatic activity of Crystal Structure of Fragment (3-(5-Chloro-1,3-Benzothiazol-2-Yl) Propanoic Acid) Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain:
3.5.1.98; Protein crystallography data
The structure of Crystal Structure of Fragment (3-(5-Chloro-1,3-Benzothiazol-2-Yl) Propanoic Acid) Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain, PDB code: 5kh3
was solved by
R.J.Harding,
A.Dong,
M.Ravichandran,
R.Ferreira De Freitas,
M.Schapira,
C.Bountra,
A.M.Edwards,
V.Santhakumar,
C.M.Arrowsmith,
Structuralgenomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5kh3:
The structure of Crystal Structure of Fragment (3-(5-Chloro-1,3-Benzothiazol-2-Yl) Propanoic Acid) Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Fragment (3-(5-Chloro-1,3-Benzothiazol-2-Yl) Propanoic Acid) Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain
(pdb code 5kh3). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Fragment (3-(5-Chloro-1,3-Benzothiazol-2-Yl) Propanoic Acid) Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain, PDB code: 5kh3: Chlorine binding site 1 out of 1 in 5kh3Go back to Chlorine Binding Sites List in 5kh3
Chlorine binding site 1 out
of 1 in the Crystal Structure of Fragment (3-(5-Chloro-1,3-Benzothiazol-2-Yl) Propanoic Acid) Bound in the Ubiquitin Binding Pocket of the HDAC6 Zinc-Finger Domain
Mono view Stereo pair view
Reference:
R.J.Harding,
R.Ferreira De Freitas,
P.Collins,
I.Franzoni,
M.Ravichandran,
H.Ouyang,
K.A.Juarez-Ornelas,
M.Lautens,
M.Schapira,
F.Von Delft,
V.Santhakumar,
C.H.Arrowsmith.
Small Molecule Antagonists of the Interaction Between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin. J. Med. Chem. V. 60 9090 2017.
Page generated: Sat Dec 12 11:56:32 2020
ISSN: ISSN 1520-4804 PubMed: 29019676 DOI: 10.1021/ACS.JMEDCHEM.7B00933 |
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