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Atomistry » Chlorine » PDB 5l55-5l77 » 5l5u | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5l55-5l77 » 5l5u » |
Chlorine in PDB 5l5u: Yeast 20S Proteasome with Human BETA5I (1-138; V31M) and Human BETA6 (97-111; 118-133) in Complex with Epoxyketone Inhibitor 17Enzymatic activity of Yeast 20S Proteasome with Human BETA5I (1-138; V31M) and Human BETA6 (97-111; 118-133) in Complex with Epoxyketone Inhibitor 17
All present enzymatic activity of Yeast 20S Proteasome with Human BETA5I (1-138; V31M) and Human BETA6 (97-111; 118-133) in Complex with Epoxyketone Inhibitor 17:
3.4.25.1; Protein crystallography data
The structure of Yeast 20S Proteasome with Human BETA5I (1-138; V31M) and Human BETA6 (97-111; 118-133) in Complex with Epoxyketone Inhibitor 17, PDB code: 5l5u
was solved by
M.Groll,
E.M.Huber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5l5u:
The structure of Yeast 20S Proteasome with Human BETA5I (1-138; V31M) and Human BETA6 (97-111; 118-133) in Complex with Epoxyketone Inhibitor 17 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Yeast 20S Proteasome with Human BETA5I (1-138; V31M) and Human BETA6 (97-111; 118-133) in Complex with Epoxyketone Inhibitor 17
(pdb code 5l5u). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Yeast 20S Proteasome with Human BETA5I (1-138; V31M) and Human BETA6 (97-111; 118-133) in Complex with Epoxyketone Inhibitor 17, PDB code: 5l5u: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 5l5uGo back to Chlorine Binding Sites List in 5l5u
Chlorine binding site 1 out
of 2 in the Yeast 20S Proteasome with Human BETA5I (1-138; V31M) and Human BETA6 (97-111; 118-133) in Complex with Epoxyketone Inhibitor 17
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 5l5uGo back to Chlorine Binding Sites List in 5l5u
Chlorine binding site 2 out
of 2 in the Yeast 20S Proteasome with Human BETA5I (1-138; V31M) and Human BETA6 (97-111; 118-133) in Complex with Epoxyketone Inhibitor 17
Mono view Stereo pair view
Reference:
E.M.Huber,
W.Heinemeyer,
G.De Bruin,
H.S.Overkleeft,
M.Groll.
A Humanized Yeast Proteasome Identifies Unique Binding Modes of Inhibitors For the Immunosubunit Beta 5I. Embo J. V. 35 2602 2016.
Page generated: Sat Dec 12 11:59:57 2020
ISSN: ESSN 1460-2075 PubMed: 27789522 DOI: 10.15252/EMBJ.201695222 |
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