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Atomistry » Chlorine » PDB 5l79-5ley » 5l9z | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5l79-5ley » 5l9z » |
Chlorine in PDB 5l9z: Crystal Structure of Human Heparanase Nucleophile Mutant (E343Q), in Complex with Unreacted Glucuronic Acid Configured Aziridine Probe JJB355Enzymatic activity of Crystal Structure of Human Heparanase Nucleophile Mutant (E343Q), in Complex with Unreacted Glucuronic Acid Configured Aziridine Probe JJB355
All present enzymatic activity of Crystal Structure of Human Heparanase Nucleophile Mutant (E343Q), in Complex with Unreacted Glucuronic Acid Configured Aziridine Probe JJB355:
3.2.1.166; Protein crystallography data
The structure of Crystal Structure of Human Heparanase Nucleophile Mutant (E343Q), in Complex with Unreacted Glucuronic Acid Configured Aziridine Probe JJB355, PDB code: 5l9z
was solved by
L.Wu,
Y.Jin,
G.J.Davies,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Heparanase Nucleophile Mutant (E343Q), in Complex with Unreacted Glucuronic Acid Configured Aziridine Probe JJB355
(pdb code 5l9z). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Human Heparanase Nucleophile Mutant (E343Q), in Complex with Unreacted Glucuronic Acid Configured Aziridine Probe JJB355, PDB code: 5l9z: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 5l9zGo back to Chlorine Binding Sites List in 5l9z
Chlorine binding site 1 out
of 3 in the Crystal Structure of Human Heparanase Nucleophile Mutant (E343Q), in Complex with Unreacted Glucuronic Acid Configured Aziridine Probe JJB355
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 5l9zGo back to Chlorine Binding Sites List in 5l9z
Chlorine binding site 2 out
of 3 in the Crystal Structure of Human Heparanase Nucleophile Mutant (E343Q), in Complex with Unreacted Glucuronic Acid Configured Aziridine Probe JJB355
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 5l9zGo back to Chlorine Binding Sites List in 5l9z
Chlorine binding site 3 out
of 3 in the Crystal Structure of Human Heparanase Nucleophile Mutant (E343Q), in Complex with Unreacted Glucuronic Acid Configured Aziridine Probe JJB355
Mono view Stereo pair view
Reference:
L.Wu,
J.Jiang,
Y.Jin,
W.W.Kallemeijn,
C.L.Kuo,
M.Artola,
W.Dai,
C.Van Elk,
M.Van Eijk,
G.A.Van Der Marel,
J.D.C.Codee,
B.I.Florea,
J.M.F.G.Aerts,
H.S.Overkleeft,
G.J.Davies.
Activity-Based Probes For Functional Interrogation of Retaining Beta-Glucuronidases. Nat. Chem. Biol. V. 13 867 2017.
Page generated: Sat Dec 12 12:01:25 2020
ISSN: ESSN 1552-4469 PubMed: 28581485 DOI: 10.1038/NCHEMBIO.2395 |
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