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Atomistry » Chlorine » PDB 5l79-5ley » 5lap » |
Chlorine in PDB 5lap: P53 Cancer Mutant Y220C with CYS182 AlkylationProtein crystallography data
The structure of P53 Cancer Mutant Y220C with CYS182 Alkylation, PDB code: 5lap
was solved by
A.C.Joerger,
M.R.Bauer,
A.R.Fersht,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5lap:
The structure of P53 Cancer Mutant Y220C with CYS182 Alkylation also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the P53 Cancer Mutant Y220C with CYS182 Alkylation
(pdb code 5lap). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the P53 Cancer Mutant Y220C with CYS182 Alkylation, PDB code: 5lap: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 5lapGo back to Chlorine Binding Sites List in 5lap
Chlorine binding site 1 out
of 2 in the P53 Cancer Mutant Y220C with CYS182 Alkylation
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 5lapGo back to Chlorine Binding Sites List in 5lap
Chlorine binding site 2 out
of 2 in the P53 Cancer Mutant Y220C with CYS182 Alkylation
Mono view Stereo pair view
Reference:
M.R.Bauer,
A.C.Joerger,
A.R.Fersht.
2-Sulfonylpyrimidines: Mild Alkylating Agents with Anticancer Activity Toward P53-Compromised Cells. Proc.Natl.Acad.Sci.Usa V. 113 E5271 2016.
Page generated: Sat Dec 12 12:01:30 2020
ISSN: ESSN 1091-6490 PubMed: 27551077 DOI: 10.1073/PNAS.1610421113 |
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