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Chlorine in PDB 5lz7: Fragment-Based Inhibitors of Lipoprotein Associated Phospholipase A2Enzymatic activity of Fragment-Based Inhibitors of Lipoprotein Associated Phospholipase A2
All present enzymatic activity of Fragment-Based Inhibitors of Lipoprotein Associated Phospholipase A2:
3.1.1.47; Protein crystallography data
The structure of Fragment-Based Inhibitors of Lipoprotein Associated Phospholipase A2, PDB code: 5lz7
was solved by
A.Woolford,
P.Day,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5lz7:
The structure of Fragment-Based Inhibitors of Lipoprotein Associated Phospholipase A2 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Fragment-Based Inhibitors of Lipoprotein Associated Phospholipase A2
(pdb code 5lz7). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Fragment-Based Inhibitors of Lipoprotein Associated Phospholipase A2, PDB code: 5lz7: Chlorine binding site 1 out of 1 in 5lz7Go back to Chlorine Binding Sites List in 5lz7
Chlorine binding site 1 out
of 1 in the Fragment-Based Inhibitors of Lipoprotein Associated Phospholipase A2
Mono view Stereo pair view
Reference:
A.J.Woolford,
P.J.Day,
V.Beneton,
V.Berdini,
J.E.Coyle,
Y.Dudit,
P.Grondin,
P.Huet,
L.Y.Lee,
E.S.Manas,
R.L.Mcmenamin,
C.W.Murray,
L.W.Page,
V.K.Patel,
F.Potvain,
S.J.Rich,
Y.Sang,
D.O.Somers,
L.Trottet,
Z.Wan,
X.Zhang.
Fragment-Based Approach to the Development of An Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2). J. Med. Chem. V. 59 10738 2016.
Page generated: Sat Dec 12 12:04:48 2020
ISSN: ISSN 1520-4804 PubMed: 27933945 DOI: 10.1021/ACS.JMEDCHEM.6B01427 |
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