Chlorine in PDB 5mhj: ICP4 Dna-Binding Domain, Lacking Intrinsically Disordered Region, in Complex with 12MER Dna Duplex From Its Own Promoter

The structure of ICP4 Dna-Binding Domain, Lacking Intrinsically Disordered Region, in Complex with 12MER Dna Duplex From Its Own Promoter, PDB code: 5mhj was solved by R.B.Tunnicliffe, M.P.Lockhart-Cairns, C.Levy, P.Mould, T.A.Jowitt, H.Sito, C.Baldock, R.M.Sandri-Goldin, A.P.Golovanov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.22 / 2.12
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	127.254, 39.084, 90.443, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / 23.5

The binding sites of Chlorine atom in the ICP4 Dna-Binding Domain, Lacking Intrinsically Disordered Region, in Complex with 12MER Dna Duplex From Its Own Promoter (pdb code 5mhj). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the ICP4 Dna-Binding Domain, Lacking Intrinsically Disordered Region, in Complex with 12MER Dna Duplex From Its Own Promoter, PDB code: 5mhj:

Chlorine binding site 1 out of 1 in the ICP4 Dna-Binding Domain, Lacking Intrinsically Disordered Region, in Complex with 12MER Dna Duplex From Its Own Promoter


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of ICP4 Dna-Binding Domain, Lacking Intrinsically Disordered Region, in Complex with 12MER Dna Duplex From Its Own Promoter within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl502 b:40.2 occ:1.00 NH1 A:ARG472 3.2 29.2 1.0 N B:SER312 3.3 28.2 1.0 O B:HOH636 3.4 25.1 1.0 NH2 A:ARG472 3.5 31.0 1.0 O B:HOH688 3.5 31.0 1.0 OG B:SER312 3.6 32.6 1.0 CZ A:ARG472 3.7 32.7 1.0 CB B:SER312 4.0 26.1 1.0 CA B:VAL311 4.0 27.8 1.0 O B:TYR310 4.2 27.0 1.0 C B:VAL311 4.2 29.0 1.0 CA B:SER312 4.3 28.5 1.0 CG1 B:VAL311 4.6 34.2 1.0 CB B:VAL311 4.9 35.6 1.0 N B:VAL311 4.9 31.3 1.0 O B:HOH656 4.9 30.2 1.0 C B:TYR310 4.9 28.8 1.0 NE A:ARG472 5.0 28.9 1.0

R.B.Tunnicliffe, M.P.Lockhart-Cairns, C.Levy, A.P.Mould, T.A.Jowitt, H.Sito, C.Baldock, R.M.Sandri-Goldin, A.P.Golovanov. The Herpes Viral Transcription Factor ICP4 Forms A Novel Dna Recognition Complex. Nucleic Acids Res. V. 45 8064 2017.
ISSN: ESSN 1362-4962
PubMed: 28505309
DOI: 10.1093/NAR/GKX419