Atomistry » Chlorine » PDB 5mgg-5mls » 5mkr
Atomistry »
  Chlorine »
    PDB 5mgg-5mls »
      5mkr »

Chlorine in PDB 5mkr: HSP72-Nbd Bound to Compound Tci 8 - TYR15 in Up-Conformation

Protein crystallography data

The structure of HSP72-Nbd Bound to Compound Tci 8 - TYR15 in Up-Conformation, PDB code: 5mkr was solved by J.Pettinger, I.M.Westwood, N.Cronin, Y.-V.Le Bihan, R.L.M.Van Montfort, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.98 / 1.87
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 50.677, 86.400, 100.232, 90.00, 90.00, 90.00
R / Rfree (%) 16.5 / 22.2

Chlorine Binding Sites:

The binding sites of Chlorine atom in the HSP72-Nbd Bound to Compound Tci 8 - TYR15 in Up-Conformation (pdb code 5mkr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the HSP72-Nbd Bound to Compound Tci 8 - TYR15 in Up-Conformation, PDB code: 5mkr:

Chlorine binding site 1 out of 1 in 5mkr

Go back to Chlorine Binding Sites List in 5mkr
Chlorine binding site 1 out of 1 in the HSP72-Nbd Bound to Compound Tci 8 - TYR15 in Up-Conformation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of HSP72-Nbd Bound to Compound Tci 8 - TYR15 in Up-Conformation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl401

b:23.5
occ:0.89
CL A:TI8401 0.0 23.5 0.9
C18 A:TI8401 1.7 16.4 0.9
C19 A:TI8401 2.7 13.0 0.9
C17 A:TI8401 2.7 14.8 0.9
NH2 A:ARG272 3.4 15.3 1.0
CZ A:ARG272 3.7 25.9 1.0
NH1 A:ARG272 3.8 13.5 1.0
C20 A:TI8401 4.0 10.8 0.9
C16 A:TI8401 4.0 12.5 0.9
O A:HOH947 4.0 30.5 1.0
NE A:ARG272 4.4 11.5 1.0
C15 A:TI8401 4.5 10.7 0.9
O A:HOH814 4.6 14.6 1.0

Reference:

J.Pettinger, Y.V.Le Bihan, M.Widya, R.L.Van Montfort, K.Jones, M.D.Cheeseman. An Irreversible Inhibitor of HSP72 That Unexpectedly Targets Lysine-56. Angew. Chem. Int. Ed. Engl. V. 56 3536 2017.
ISSN: ESSN 1521-3773
PubMed: 28225177
DOI: 10.1002/ANIE.201611907
Page generated: Fri Jul 26 12:45:42 2024

Last articles

Ca in 5MFN
Ca in 5MFH
Ca in 5MFE
Ca in 5MFG
Ca in 5MFA
Ca in 5MF4
Ca in 5MEY
Ca in 5MB1
Ca in 5MAZ
Ca in 5MER
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy