Chlorine in PDB 5ml9: Cocrystal Structure of Fc Gamma Receptor Iiia Interacting with Affimer F4, A Specific Binding Protein Which Blocks Igg Binding to the Receptor.

The structure of Cocrystal Structure of Fc Gamma Receptor Iiia Interacting with Affimer F4, A Specific Binding Protein Which Blocks Igg Binding to the Receptor., PDB code: 5ml9 was solved by J.I.Robinson, D.C.Tomlinson, E.W.Baxter, R.L.Owen, M.Thomsen, S.J.Win, J.E.Nettleship, C.Tiede, R.J.Foster, M.P.Waterhouse, S.A.Harris, R.J.Owens, C.W.G.Fishwick, A.Goldman, M.J.Mcpherson, A.W.Morgan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.74 / 2.35
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	56.481, 72.587, 96.451, 90.00, 90.00, 90.00
R / Rfree (%)	21.9 / 27.2

The binding sites of Chlorine atom in the Cocrystal Structure of Fc Gamma Receptor Iiia Interacting with Affimer F4, A Specific Binding Protein Which Blocks Igg Binding to the Receptor. (pdb code 5ml9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cocrystal Structure of Fc Gamma Receptor Iiia Interacting with Affimer F4, A Specific Binding Protein Which Blocks Igg Binding to the Receptor., PDB code: 5ml9:

Chlorine binding site 1 out of 1 in the Cocrystal Structure of Fc Gamma Receptor Iiia Interacting with Affimer F4, A Specific Binding Protein Which Blocks Igg Binding to the Receptor.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cocrystal Structure of Fc Gamma Receptor Iiia Interacting with Affimer F4, A Specific Binding Protein Which Blocks Igg Binding to the Receptor. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl210 b:50.4 occ:1.00 HE22 A:GLN15 2.6 37.5 1.0 ND1 A:HIS107 3.3 36.3 1.0 NE2 A:GLN15 3.4 31.2 1.0 HE1 A:TYR140 3.4 43.6 1.0 HE21 A:GLN15 3.8 37.5 1.0 HE1 A:HIS107 4.1 46.0 1.0 CE1 A:HIS107 4.1 38.3 1.0 HB2 A:HIS107 4.1 45.4 1.0 OE1 A:GLN15 4.1 39.1 1.0 CD A:GLN15 4.2 44.5 1.0 CG A:HIS107 4.3 27.1 1.0 CE1 A:TYR140 4.3 36.2 1.0 HB3 A:HIS107 4.4 45.4 1.0 HH11 B:ARG9 4.4 66.4 1.0 CB A:HIS107 4.5 37.8 1.0 HD2 B:ARG9 4.8 52.3 1.0 OH A:TYR140 4.9 41.4 1.0 NH1 B:ARG9 4.9 55.2 1.0 HD1 A:TYR140 5.0 29.8 1.0 HH12 B:ARG9 5.0 66.4 1.0

J.I.Robinson, E.W.Baxter, R.L.Owen, M.Thomsen, D.C.Tomlinson, M.P.Waterhouse, S.J.Win, J.E.Nettleship, C.Tiede, R.J.Foster, R.J.Owens, C.W.G.Fishwick, S.A.Harris, A.Goldman, M.J.Mcpherson, A.W.Morgan. Affimer Proteins Inhibit Immune Complex Binding to Fc Gamma Riiia with High Specificity Through Competitive and Allosteric Modes of Action. Proc. Natl. Acad. Sci. V. 115 E72 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29247053
DOI: 10.1073/PNAS.1707856115