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Atomistry » Chlorine » PDB 5mlr-5mtf » 5mo7 » |
Chlorine in PDB 5mo7: Crystal Structure of CK2ALPHA with N-(3-(((2-Chloro-[1,1'-Biphenyl]-4- Yl)Methyl)Amino)Propyl)Methanesulfonamide BoundEnzymatic activity of Crystal Structure of CK2ALPHA with N-(3-(((2-Chloro-[1,1'-Biphenyl]-4- Yl)Methyl)Amino)Propyl)Methanesulfonamide Bound
All present enzymatic activity of Crystal Structure of CK2ALPHA with N-(3-(((2-Chloro-[1,1'-Biphenyl]-4- Yl)Methyl)Amino)Propyl)Methanesulfonamide Bound:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of CK2ALPHA with N-(3-(((2-Chloro-[1,1'-Biphenyl]-4- Yl)Methyl)Amino)Propyl)Methanesulfonamide Bound, PDB code: 5mo7
was solved by
P.Brear,
C.De Fusco,
K.Georgiou,
J.Iegre,
H.Sore,
M.Hyvonen,
D.Spring,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of CK2ALPHA with N-(3-(((2-Chloro-[1,1'-Biphenyl]-4- Yl)Methyl)Amino)Propyl)Methanesulfonamide Bound
(pdb code 5mo7). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of CK2ALPHA with N-(3-(((2-Chloro-[1,1'-Biphenyl]-4- Yl)Methyl)Amino)Propyl)Methanesulfonamide Bound, PDB code: 5mo7: Chlorine binding site 1 out of 1 in 5mo7Go back to Chlorine Binding Sites List in 5mo7
Chlorine binding site 1 out
of 1 in the Crystal Structure of CK2ALPHA with N-(3-(((2-Chloro-[1,1'-Biphenyl]-4- Yl)Methyl)Amino)Propyl)Methanesulfonamide Bound
Mono view Stereo pair view
Reference:
C.De Fusco,
P.Brear,
J.Iegre,
K.H.Georgiou,
H.F.Sore,
M.Hyvonen,
D.R.Spring.
A Fragment-Based Approach Leading to the Discovery of A Novel Binding Site and the Selective CK2 Inhibitor CAM4066. Bioorg. Med. Chem. V. 25 3471 2017.
Page generated: Sat Dec 12 12:06:54 2020
ISSN: ESSN 1464-3391 PubMed: 28495381 DOI: 10.1016/J.BMC.2017.04.037 |
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