Chlorine in PDB 5mqz: Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform

All present enzymatic activity of Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform:
2.6.1.42;

The structure of Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform, PDB code: 5mqz was solved by P.James, M.N.Isupov, C.Sayer, J.A.Littlechild, J.M.Sutter, M.Schmidt, P.Schoenheit, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	66.86 / 2.10
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	72.920, 139.120, 167.570, 90.00, 90.00, 90.00
R / Rfree (%)	18.1 / 21.8

The binding sites of Chlorine atom in the Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform (pdb code 5mqz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform, PDB code: 5mqz:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:31.8 occ:0.80 O B:HOH467 2.7 49.6 1.0 O B:HOH475 2.9 26.2 1.0 O A:HOH477 3.1 23.1 1.0 N B:SER141 3.2 24.7 1.0 N A:SER141 3.2 25.8 1.0 CB B:SER141 3.6 28.4 1.0 CB A:SER141 3.6 24.7 1.0 CB A:ALA144 3.7 24.8 1.0 CB B:ALA144 3.8 25.7 1.0 CA B:ASN140 3.9 27.1 1.0 CA B:SER141 4.0 28.7 1.0 CA A:SER141 4.0 23.8 1.0 C B:ASN140 4.0 24.9 1.0 CA A:ASN140 4.0 24.2 1.0 C A:ASN140 4.1 26.1 1.0 O B:ARG139 4.5 26.4 1.0 O A:ARG139 4.6 25.0 1.0 OD1 A:ASN140 4.9 34.0 1.0 OD1 B:ASN140 4.9 29.8 1.0 CB B:ASN140 4.9 24.8 1.0 OG B:SER141 4.9 30.3 1.0 O A:HOH419 4.9 35.3 1.0 N B:ASN140 4.9 27.0 1.0 CB A:ASN140 4.9 26.4 1.0 OG A:SER141 4.9 30.4 1.0 O B:HOH408 5.0 29.9 1.0

Chlorine binding site 2 out of 3 in the Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl301 b:32.3 occ:0.80 O D:HOH428 2.8 50.4 1.0 O D:HOH472 3.0 22.7 1.0 O C:HOH467 3.1 25.8 1.0 N C:SER141 3.1 28.3 1.0 N D:SER141 3.2 25.5 1.0 CB C:SER141 3.6 27.3 1.0 CB D:SER141 3.7 23.2 1.0 CB C:ALA144 3.8 26.2 1.0 CB D:ALA144 3.8 28.6 1.0 CA C:ASN140 3.9 24.3 1.0 CA D:ASN140 4.0 23.5 1.0 CA C:SER141 4.0 27.6 1.0 C C:ASN140 4.0 26.7 1.0 CA D:SER141 4.0 22.2 1.0 C D:ASN140 4.1 29.0 1.0 O C:ARG139 4.5 21.5 1.0 O D:ARG139 4.6 24.3 1.0 CB C:ASN140 4.8 27.4 1.0 OD1 D:ASN140 4.8 33.7 1.0 OD1 C:ASN140 4.8 36.0 1.0 O C:HOH414 4.9 30.5 1.0 CB D:ASN140 4.9 23.0 1.0 N C:ASN140 4.9 25.7 1.0 O D:HOH407 4.9 28.1 1.0 N D:ASN140 4.9 24.7 1.0 OG C:SER141 5.0 36.6 1.0 OG D:SER141 5.0 31.4 1.0

Chlorine binding site 3 out of 3 in the Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Archaeal Branched-Chain Amino Acid Aminotransferase From Archaeoglobus Fulgidus; Holoform within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl301 b:33.4 occ:0.80 O E:HOH444 2.8 45.6 1.0 O F:HOH365 2.9 30.3 1.0 O E:HOH484 2.9 32.6 1.0 N F:SER141 3.1 28.9 1.0 N E:SER141 3.2 26.6 1.0 CB F:SER141 3.5 30.8 1.0 CB E:SER141 3.6 28.2 1.0 CB E:ALA144 3.7 25.4 1.0 CB F:ALA144 3.8 26.3 1.0 CA F:SER141 3.9 29.1 1.0 CA F:ASN140 4.0 26.1 1.0 C F:ASN140 4.0 29.6 1.0 CA E:SER141 4.0 30.6 1.0 CA E:ASN140 4.1 24.3 1.0 C E:ASN140 4.1 29.5 1.0 O F:ARG139 4.5 24.9 1.0 O E:ARG139 4.6 21.5 1.0 OG F:SER141 4.9 33.4 1.0 O E:HOH405 4.9 33.6 1.0 OD1 F:ASN140 4.9 36.5 1.0 CB F:ASN140 4.9 29.8 1.0 OG E:SER141 4.9 32.7 1.0 OD1 E:ASN140 4.9 32.8 1.0 N F:ASN140 4.9 25.5 1.0 O F:HOH310 4.9 32.6 1.0 CB E:ASN140 5.0 24.9 1.0

P.James, M.N.Isupov, C.Sayer, J.A.Littlechild, J.M.Sutter, M.Schmidt, P.Schoenheit. Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation To Be Published.