Atomistry » Chlorine » PDB 5mlr-5mtf » 5mr0
Atomistry »
  Chlorine »
    PDB 5mlr-5mtf »
      5mr0 »

Chlorine in PDB 5mr0: Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation

Enzymatic activity of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation

All present enzymatic activity of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation:
2.6.1.42;

Protein crystallography data

The structure of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation, PDB code: 5mr0 was solved by M.N.Isupov, J.A.Littlechild, P.James, C.Sayer, J.M.Sutter, M.Schmidt, P.Schoenheit, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 64.72 / 1.98
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 73.210, 140.230, 168.320, 90.00, 90.00, 90.00
R / Rfree (%) 18 / 20.9

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation (pdb code 5mr0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 9 binding sites of Chlorine where determined in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation, PDB code: 5mr0:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9;

Chlorine binding site 1 out of 9 in 5mr0

Go back to Chlorine Binding Sites List in 5mr0
Chlorine binding site 1 out of 9 in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl302

b:27.1
occ:0.80
 O B:HOH452 2.7 40.2 1.0
O B:HOH490 2.9 24.6 1.0
O A:HOH472 3.0 22.1 1.0
N A:SER141 3.2 23.9 1.0
N B:SER141 3.2 25.7 1.0
CB A:SER141 3.6 26.2 1.0
CB B:SER141 3.6 27.6 1.0
CB A:ALA144 3.8 23.0 1.0
CB B:ALA144 3.9 21.4 1.0
CA B:ASN140 4.0 28.8 1.0
CA A:ASN140 4.0 22.0 1.0
CA A:SER141 4.0 23.2 1.0
CA B:SER141 4.0 26.3 1.0
C B:ASN140 4.0 28.7 1.0
C A:ASN140 4.1 24.3 1.0
O B:ARG139 4.5 25.2 1.0
O A:ARG139 4.6 22.5 1.0
OD1 B:ASN140 4.9 27.4 1.0
CB B:ASN140 4.9 25.2 1.0
OD1 A:ASN140 4.9 28.9 1.0
N B:ASN140 4.9 23.4 1.0
OG A:SER141 4.9 30.2 1.0
CB A:ASN140 4.9 23.7 1.0
OG B:SER141 4.9 26.6 1.0
O A:HOH446 5.0 28.4 1.0

Chlorine binding site 2 out of 9 in 5mr0

Go back to Chlorine Binding Sites List in 5mr0
Chlorine binding site 2 out of 9 in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl303

b:33.8
occ:0.70
 O5 C:TAM307 2.7 65.3 0.6
O C:HOH446 3.0 24.4 1.0
O A:HOH448 3.1 36.9 1.0
O A:HOH492 3.2 39.3 1.0
ND2 A:ASN229 3.2 29.3 1.0
CB A:ASN229 3.6 27.3 1.0
C5 C:TAM307 3.7 47.6 0.6
C3 C:TAM307 3.7 45.2 0.6
CG C:PRO201 3.8 27.8 1.0
CG2 C:ILE203 3.9 28.0 1.0
C2 C:TAM307 3.9 51.6 0.6
CG A:ASN229 3.9 34.0 1.0
CB C:PRO201 4.1 27.2 1.0
ND2 C:ASN229 4.3 25.4 1.0
OD1 C:ASN229 4.5 30.6 1.0
C C:TAM307 4.5 57.8 0.6
CE1 A:TYR180 4.6 25.1 1.0
O A:HOH425 4.6 28.8 1.0
N A:ASN229 4.7 28.1 1.0
C6 C:TAM307 4.7 47.9 0.6
CD C:PRO201 4.7 27.8 1.0
CA A:ASN229 4.7 27.9 1.0
OH A:TYR180 4.8 25.2 1.0
CG C:ASN229 4.8 31.6 1.0
CZ A:TYR180 4.8 27.8 1.0
O C:HOH420 4.9 33.1 1.0

Chlorine binding site 3 out of 9 in 5mr0

Go back to Chlorine Binding Sites List in 5mr0
Chlorine binding site 3 out of 9 in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl302

b:32.7
occ:0.60
 O5 B:TAM306 2.9 58.0 0.6
O E:HOH441 3.0 26.6 1.0
O E:HOH472 3.2 41.0 1.0
ND2 B:ASN229 3.3 27.2 1.0
O B:HOH441 3.4 33.2 1.0
C3 B:TAM306 3.5 46.5 0.6
CB B:ASN229 3.7 29.3 1.0
CG E:PRO201 3.8 28.2 1.0
CG B:ASN229 4.0 32.7 1.0
CG2 E:ILE203 4.0 30.0 1.0
CB E:PRO201 4.1 29.6 1.0
C5 B:TAM306 4.2 50.4 0.6
C2 B:TAM306 4.2 42.6 0.6
ND2 E:ASN229 4.2 26.2 1.0
C6 B:TAM306 4.2 40.9 0.6
OD1 E:ASN229 4.5 26.9 1.0
C B:TAM306 4.5 57.0 0.6
O B:HOH422 4.6 24.7 1.0
CE1 B:TYR180 4.6 28.8 1.0
CD E:PRO201 4.7 27.4 1.0
N B:ASN229 4.7 26.6 1.0
CG E:ASN229 4.7 32.5 1.0
CA B:ASN229 4.8 28.7 1.0
OH B:TYR180 4.8 28.7 1.0
O E:HOH408 4.8 30.2 1.0
CZ B:TYR180 4.8 27.4 1.0

Chlorine binding site 4 out of 9 in 5mr0

Go back to Chlorine Binding Sites List in 5mr0
Chlorine binding site 4 out of 9 in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl302

b:29.1
occ:0.80
 O D:HOH442 2.8 40.8 1.0
O D:HOH496 2.9 24.3 1.0
O C:HOH485 3.0 21.8 1.0
N D:SER141 3.2 23.7 1.0
N C:SER141 3.2 25.0 1.0
CB C:SER141 3.6 28.2 1.0
CB D:SER141 3.6 23.6 1.0
CB C:ALA144 3.8 22.6 1.0
CB D:ALA144 3.9 24.6 1.0
CA D:ASN140 3.9 19.7 1.0
CA C:ASN140 4.0 24.7 1.0
CA D:SER141 4.0 24.6 1.0
CA C:SER141 4.0 25.9 1.0
C D:ASN140 4.0 25.4 1.0
C C:ASN140 4.1 27.6 1.0
O D:ARG139 4.5 21.9 1.0
O C:ARG139 4.6 24.0 1.0
OD1 D:ASN140 4.8 30.7 1.0
O C:HOH441 4.9 26.0 1.0
CB D:ASN140 4.9 21.4 1.0
N D:ASN140 4.9 23.2 1.0
CB C:ASN140 4.9 25.0 1.0
OD1 C:ASN140 4.9 28.1 1.0
OG C:SER141 4.9 34.0 1.0
O D:HOH416 5.0 24.5 1.0
OG D:SER141 5.0 27.0 1.0
N C:ASN140 5.0 22.2 1.0

Chlorine binding site 5 out of 9 in 5mr0

Go back to Chlorine Binding Sites List in 5mr0
Chlorine binding site 5 out of 9 in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl303

b:31.3
occ:0.70
 O6 C:TAM307 2.8 70.6 0.6
O F:HOH437 3.1 28.8 1.0
ND2 C:ASN229 3.1 25.4 1.0
O C:HOH470 3.2 43.4 1.0
O C:HOH438 3.5 34.6 1.0
CB C:ASN229 3.6 26.1 1.0
C1 C:TAM307 3.6 40.0 0.6
C3 C:TAM307 3.8 45.2 0.6
C6 C:TAM307 3.8 47.9 0.6
CG C:ASN229 3.8 31.6 1.0
CG2 F:ILE203 3.9 28.4 1.0
CG F:PRO201 3.9 36.9 1.0
CB F:PRO201 4.2 32.0 1.0
C C:TAM307 4.4 57.8 0.6
ND2 F:ASN229 4.4 25.2 1.0
CE1 C:TYR180 4.5 23.5 1.0
O C:HOH422 4.6 26.6 1.0
OD1 F:ASN229 4.6 29.5 1.0
OH C:TYR180 4.6 25.8 1.0
CZ C:TYR180 4.7 31.5 1.0
N C:ASN229 4.7 29.2 1.0
CA C:ASN229 4.7 32.0 1.0
C4 C:TAM307 4.7 47.4 0.6
CD F:PRO201 4.9 34.4 1.0
CG F:ASN229 4.9 34.1 1.0
O F:HOH413 5.0 33.5 1.0

Chlorine binding site 6 out of 9 in 5mr0

Go back to Chlorine Binding Sites List in 5mr0
Chlorine binding site 6 out of 9 in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl302

b:31.3
occ:0.70
 O4 B:TAM306 2.8 67.8 0.6
O B:HOH465 3.0 30.7 1.0
O D:HOH467 3.1 39.9 1.0
ND2 D:ASN229 3.2 27.3 1.0
O D:HOH483 3.4 31.9 1.0
C2 B:TAM306 3.6 42.6 0.6
CB D:ASN229 3.7 23.4 1.0
CG B:PRO201 3.8 35.3 1.0
C1 B:TAM306 3.8 46.9 0.6
C4 B:TAM306 3.9 45.0 0.6
CG D:ASN229 3.9 33.3 1.0
CG2 B:ILE203 4.0 28.5 1.0
CB B:PRO201 4.1 26.4 1.0
ND2 B:ASN229 4.3 27.2 1.0
C B:TAM306 4.3 57.0 0.6
OD1 B:ASN229 4.6 27.1 1.0
CE1 D:TYR180 4.6 23.2 1.0
N D:ASN229 4.7 23.6 1.0
O D:HOH430 4.7 25.1 1.0
OH D:TYR180 4.7 27.6 1.0
CA D:ASN229 4.7 27.9 1.0
CZ D:TYR180 4.8 25.9 1.0
C5 B:TAM306 4.8 50.4 0.6
CD B:PRO201 4.8 32.2 1.0
CG B:ASN229 4.8 32.7 1.0
O E:HOH452 4.9 32.9 1.0
O B:HOH412 5.0 30.4 1.0
OG1 D:THR228 5.0 39.2 1.0

Chlorine binding site 7 out of 9 in 5mr0

Go back to Chlorine Binding Sites List in 5mr0
Chlorine binding site 7 out of 9 in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cl302

b:29.4
occ:0.80
 O E:HOH444 2.9 36.4 1.0
O F:HOH481 2.9 26.8 1.0
O E:HOH486 3.0 25.6 1.0
N F:SER141 3.2 24.7 1.0
N E:SER141 3.2 23.5 1.0
CB F:SER141 3.6 26.5 1.0
CB E:SER141 3.6 25.5 1.0
CB E:ALA144 3.8 25.3 1.0
CB F:ALA144 3.9 24.5 1.0
CA F:SER141 4.0 23.0 1.0
CA F:ASN140 4.0 25.2 1.0
CA E:ASN140 4.0 25.8 1.0
CA E:SER141 4.0 24.1 1.0
C F:ASN140 4.0 29.7 1.0
C E:ASN140 4.1 28.1 1.0
O F:ARG139 4.5 25.6 1.0
O E:ARG139 4.6 24.7 1.0
O E:HOH414 4.9 26.8 1.0
O F:HOH407 4.9 28.5 1.0
OG F:SER141 4.9 25.8 1.0
OG E:SER141 4.9 24.5 1.0
CB F:ASN140 4.9 33.0 1.0
OD1 F:ASN140 4.9 34.9 1.0
OD1 E:ASN140 4.9 29.6 1.0
CB E:ASN140 5.0 25.9 1.0
N F:ASN140 5.0 26.8 1.0
N E:ASN140 5.0 23.5 1.0

Chlorine binding site 8 out of 9 in 5mr0

Go back to Chlorine Binding Sites List in 5mr0
Chlorine binding site 8 out of 9 in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cl303

b:33.1
occ:0.70
 O6 B:TAM306 2.9 60.6 0.6
O D:HOH427 3.1 24.9 1.0
O E:HOH452 3.2 32.9 1.0
ND2 E:ASN229 3.3 26.2 1.0
O E:HOH449 3.3 38.2 1.0
CB E:ASN229 3.7 22.7 1.0
C1 B:TAM306 3.7 46.9 0.6
C6 B:TAM306 3.7 40.9 0.6
C3 B:TAM306 3.8 46.5 0.6
CG D:PRO201 3.8 26.9 1.0
CG E:ASN229 4.0 32.5 1.0
CG2 D:ILE203 4.0 29.7 1.0
CB D:PRO201 4.1 27.3 1.0
ND2 D:ASN229 4.3 27.3 1.0
C B:TAM306 4.4 57.0 0.6
OD1 D:ASN229 4.5 26.3 1.0
N E:ASN229 4.6 23.6 1.0
CE1 E:TYR180 4.7 27.1 1.0
CA E:ASN229 4.7 25.3 1.0
O E:HOH415 4.7 27.6 1.0
C4 B:TAM306 4.7 45.0 0.6
CD D:PRO201 4.8 26.9 1.0
CG D:ASN229 4.8 33.3 1.0
OH E:TYR180 4.8 27.6 1.0
CZ E:TYR180 4.8 27.7 1.0
OG1 E:THR228 4.9 41.1 1.0
O E:HOH472 5.0 41.0 1.0

Chlorine binding site 9 out of 9 in 5mr0

Go back to Chlorine Binding Sites List in 5mr0
Chlorine binding site 9 out of 9 in the Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of Thermophilic Archaeal Branched-Chain Amino Acid Transaminases From Geoglobus Acetivorans and Archaeoglobus Fulgidus: Biochemical and Structural Characterisation within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Cl301

b:33.5
occ:0.60
 O A:HOH442 3.0 24.4 1.0
O A:HOH476 3.1 35.0 1.0
ND2 F:ASN229 3.2 25.2 1.0
C4 C:TAM307 3.4 47.4 0.6
O4 C:TAM307 3.4 73.0 0.6
C2 C:TAM307 3.6 51.6 0.6
CB F:ASN229 3.6 26.1 1.0
O F:HOH420 3.7 41.0 1.0
CG A:PRO201 3.8 31.7 1.0
CG F:ASN229 3.9 34.1 1.0
CG2 A:ILE203 3.9 31.1 1.0
CB A:PRO201 4.1 30.9 1.0
C1 C:TAM307 4.2 40.0 0.6
ND2 A:ASN229 4.3 29.3 1.0
C5 C:TAM307 4.4 47.6 0.6
OD1 A:ASN229 4.4 32.3 1.0
C C:TAM307 4.6 57.8 0.6
O F:HOH426 4.6 30.6 1.0
CE1 F:TYR180 4.6 31.5 1.0
N F:ASN229 4.6 27.5 1.0
CD A:PRO201 4.7 29.0 1.0
CA F:ASN229 4.7 29.6 1.0
CG A:ASN229 4.7 34.0 1.0
OH F:TYR180 4.8 31.4 1.0
CZ F:TYR180 4.8 30.8 1.0
O A:HOH426 4.8 32.5 1.0
O C:HOH470 5.0 43.4 1.0

Reference:

M.N.Isupov, K.M.Boyko, J.M.Sutter, P.James, C.Sayer, M.Schmidt, P.Schonheit, A.Y.Nikolaeva, T.N.Stekhanova, A.V.Mardanov, N.V.Ravin, E.Y.Bezsudnova, V.O.Popov, J.A.Littlechild. Thermostable Branched-Chain Amino Acid Transaminases From the Archaeageoglobus Acetivoransandarchaeoglobus Fulgidus: Biochemical and Structural Characterization. Front Bioeng Biotechnol V. 7 7 2019.
ISSN: ISSN 2296-4185
PubMed: 30733943
DOI: 10.3389/FBIOE.2019.00007
Page generated: Sat Dec 12 12:07:05 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy