|
Chlorine in PDB 5orx: Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding FragmentEnzymatic activity of Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment
All present enzymatic activity of Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment, PDB code: 5orx
was solved by
P.J.Mcintyre,
P.M.Collins,
F.Von Delft,
R.Bayliss,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5orx:
The structure of Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment
(pdb code 5orx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment, PDB code: 5orx: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 5orxGo back to Chlorine Binding Sites List in 5orx
Chlorine binding site 1 out
of 2 in the Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 5orxGo back to Chlorine Binding Sites List in 5orx
Chlorine binding site 2 out
of 2 in the Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment
Mono view Stereo pair view
Reference:
P.J.Mcintyre,
P.M.Collins,
L.Vrzal,
K.Birchall,
L.H.Arnold,
C.Mpamhanga,
P.J.Coombs,
S.G.Burgess,
M.W.Richards,
A.Winter,
V.Veverka,
F.V.Delft,
A.Merritt,
R.Bayliss.
Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. Acs Chem. Biol. V. 12 2906 2017.
Page generated: Sat Dec 12 12:13:30 2020
ISSN: ESSN 1554-8937 PubMed: 29045126 DOI: 10.1021/ACSCHEMBIO.7B00537 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |