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Chlorine in PDB 5os0: Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding FragmentEnzymatic activity of Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment
All present enzymatic activity of Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment, PDB code: 5os0
was solved by
P.J.Mcintyre,
P.M.Collins,
F.Von Delft,
R.Bayliss,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5os0:
The structure of Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment
(pdb code 5os0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment, PDB code: 5os0: Chlorine binding site 1 out of 1 in 5os0Go back to Chlorine Binding Sites List in 5os0
Chlorine binding site 1 out
of 1 in the Crystal Structure of Aurora-A Kinase in Complex with An Allosterically Binding Fragment
Mono view Stereo pair view
Reference:
P.J.Mcintyre,
P.M.Collins,
L.Vrzal,
K.Birchall,
L.H.Arnold,
C.Mpamhanga,
P.J.Coombs,
S.G.Burgess,
M.W.Richards,
A.Winter,
V.Veverka,
F.V.Delft,
A.Merritt,
R.Bayliss.
Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches. Acs Chem. Biol. V. 12 2906 2017.
Page generated: Sat Dec 12 12:13:32 2020
ISSN: ESSN 1554-8937 PubMed: 29045126 DOI: 10.1021/ACSCHEMBIO.7B00537 |
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