Chlorine in PDB 5owr: Human STK10 Bound to Dasatinib

All present enzymatic activity of Human STK10 Bound to Dasatinib:
2.7.11.1;

The structure of Human STK10 Bound to Dasatinib, PDB code: 5owr was solved by M.Szklarz, J.R.C.Muniz, M.Vollmar, F.Von Delft, C.Bountra, S.Knapp, A.M.Edwards, C.Arrowsmith, J.M.Elkins, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	85.58 / 2.30
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	49.740, 111.720, 133.150, 90.00, 90.00, 90.00
R / Rfree (%)	22 / 25.4

The structure of Human STK10 Bound to Dasatinib also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Chlorine atom in the Human STK10 Bound to Dasatinib (pdb code 5owr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human STK10 Bound to Dasatinib, PDB code: 5owr:

Chlorine binding site 1 out of 1 in the Human STK10 Bound to Dasatinib


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human STK10 Bound to Dasatinib within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:86.8 occ:1.00 CL A:1N1401 0.0 86.8 1.0 C5 A:1N1401 1.7 83.0 1.0 C6 A:1N1401 2.7 82.2 1.0 C4 A:1N1401 2.7 79.8 1.0 N2 A:1N1401 3.0 70.5 1.0 CB A:ASP175 3.7 46.7 1.0 C3 A:1N1401 3.7 65.0 1.0 O A:HOH541 3.9 36.4 1.0 C7 A:1N1401 4.0 82.5 1.0 N A:ASP175 4.0 39.3 1.0 C9 A:1N1401 4.0 83.6 1.0 CG A:ASP175 4.1 50.8 1.0 O A:1N1401 4.1 62.3 1.0 CA A:ASP175 4.1 42.6 1.0 OD2 A:ASP175 4.3 51.9 1.0 CB A:ALA174 4.4 34.5 1.0 C8 A:1N1401 4.5 83.8 1.0 OD1 A:ASP175 4.7 51.6 1.0 C2 A:1N1401 4.7 63.1 1.0 C A:ALA174 4.9 36.2 1.0 OD1 A:ASN162 4.9 37.4 1.0

J.M.Elkins, M.Szklarz, J.R.C.Muniz, M.Vollmar, F.Von Delft, C.Bountra, S.Knapp, A.M.Edwards, C.Arrowsmith, J.M.Elkins. N/A N/A.