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Atomistry » Chlorine » PDB 5pb3-5q29 » 5pzr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 5pb3-5q29 » 5pzr » |
Chlorine in PDB 5pzr: Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]UreaEnzymatic activity of Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea
All present enzymatic activity of Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea:
3.1.3.11; Protein crystallography data
The structure of Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea, PDB code: 5pzr
was solved by
A.Ruf,
C.Joseph,
A.Alker,
D.Banner,
T.Tetaz,
J.Benz,
B.Kuhn,
M.G.Rudolph,
H.Yang,
C.Shao,
S.K.Burley,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea
(pdb code 5pzr). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea, PDB code: 5pzr: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 5pzrGo back to Chlorine Binding Sites List in 5pzr
Chlorine binding site 1 out
of 4 in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 5pzrGo back to Chlorine Binding Sites List in 5pzr
Chlorine binding site 2 out
of 4 in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 5pzrGo back to Chlorine Binding Sites List in 5pzr
Chlorine binding site 3 out
of 4 in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 5pzrGo back to Chlorine Binding Sites List in 5pzr
Chlorine binding site 4 out
of 4 in the Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea
Mono view Stereo pair view
Reference:
A.Ruf,
C.Joseph,
A.Alker,
D.Banner,
T.Tetaz,
J.Benz,
B.Kuhn,
M.G.Rudolph.
Human Liver Fructose-1,6-Bisphosphatase 1 (Fructose 1,6-Bisphosphate 1-Phosphatase, E.C.3.1.3.11) Complexed with the Allosteric Inhibitor 1-(3-Chlorophenyl)Sulfonyl-3-[3-[3-[(3-Chlorophenyl) Sulfonylcarbamoylamino]Propoxy]Propyl]Urea To Be Published.
Page generated: Sat Dec 12 12:15:22 2020
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