Chlorine in PDB 5s5v: Tubulin-Z32386228-Complex

The structure of Tubulin-Z32386228-Complex, PDB code: 5s5v was solved by T.Muehlethaler, D.Gioia, A.E.Prota, M.E.Sharpe, A.Cavalli, M.O.Steinmetz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	72.87 / 2.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	105.23, 159.54, 179.08, 90, 90, 90
R / Rfree (%)	21.7 / 26.7

The structure of Tubulin-Z32386228-Complex also contains other interesting chemical elements:

Magnesium	(Mg)	5 atoms
Calcium	(Ca)	4 atoms

The binding sites of Chlorine atom in the Tubulin-Z32386228-Complex (pdb code 5s5v). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Tubulin-Z32386228-Complex, PDB code: 5s5v:

Chlorine binding site 1 out of 1 in the Tubulin-Z32386228-Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Tubulin-Z32386228-Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl505 b:77.1 occ:0.80 CL1 B:HR8505 0.0 77.1 0.8 C5 B:HR8505 1.7 78.6 0.8 C4 B:HR8505 2.7 79.9 0.8 C6 B:HR8505 2.7 80.9 0.8 H3 B:HR8505 2.8 97.2 0.8 H2 B:HR8505 2.8 96.0 0.8 CD1 B:LEU227 3.4 77.5 1.0 C B:THR223 3.4 82.1 1.0 O B:THR223 3.5 83.7 1.0 CD2 B:LEU227 3.6 74.5 1.0 O B:PRO222 3.7 84.4 1.0 C B:PRO222 3.7 84.2 1.0 N B:TYR224 3.7 81.0 1.0 CA B:THR223 3.8 81.7 1.0 N B:THR223 3.8 85.1 1.0 C3 B:HR8505 4.0 78.5 0.8 CB B:PRO222 4.0 83.5 1.0 C7 B:HR8505 4.0 81.8 0.8 CG B:LEU227 4.1 76.0 1.0 CD2 B:TYR210 4.1 83.8 1.0 CA B:TYR224 4.4 78.5 1.0 C2 B:HR8505 4.5 82.0 0.8 CA B:PRO222 4.5 84.1 1.0 CE2 B:TYR210 4.5 89.7 1.0 CD1 B:TYR224 4.6 74.4 1.0 H8 B:HR8505 4.7 94.3 0.8 CG1 B:VAL177 4.8 81.6 1.0 CE1 B:TYR224 5.0 72.1 1.0 CG B:TYR224 5.0 74.5 1.0

T.Muhlethaler, D.Gioia, A.E.Prota, M.E.Sharpe, A.Cavalli, M.O.Steinmetz. Comprehensive Analysis of Binding Sites in Tubulin. Angew.Chem.Int.Ed.Engl. V. 60 13331 2021.
ISSN: ESSN 1521-3773
PubMed: 33951246
DOI: 10.1002/ANIE.202100273