Atomistry » Chlorine » PDB 5s2w-5sd8 » 5sb8
Atomistry »
  Chlorine »
    PDB 5s2w-5sd8 »
      5sb8 »

Chlorine in PDB 5sb8: Tubulin-Maytansinoid-3-Complex

Protein crystallography data

The structure of Tubulin-Maytansinoid-3-Complex, PDB code: 5sb8 was solved by P.Marzullo, Z.Boiarska, H.Perez-Pena, A.-C.Abel, B.Alvarez-Bernad, D.Lucena-Agell, F.Vasile, M.Sironi, M.O.Steinmetz, A.E.Prota, J.F.Diaz, S.Pieraccini, D.Passarella, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.66 / 2.30
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 104.664, 157.491, 181.511, 90, 90, 90
R / Rfree (%) 19.3 / 23

Other elements in 5sb8:

The structure of Tubulin-Maytansinoid-3-Complex also contains other interesting chemical elements:

Magnesium (Mg) 5 atoms
Calcium (Ca) 3 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Tubulin-Maytansinoid-3-Complex (pdb code 5sb8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Tubulin-Maytansinoid-3-Complex, PDB code: 5sb8:

Chlorine binding site 1 out of 1 in 5sb8

Go back to Chlorine Binding Sites List in 5sb8
Chlorine binding site 1 out of 1 in the Tubulin-Maytansinoid-3-Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Tubulin-Maytansinoid-3-Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl503

b:107.1
occ:1.00
CL33 D:5IS503 0.0 107.1 1.0
C6 D:5IS503 1.8 94.8 1.0
C1 D:5IS503 2.7 96.1 1.0
C5 D:5IS503 2.8 96.9 1.0
O34 D:5IS503 2.9 97.9 1.0
N31 D:5IS503 3.2 99.9 1.0
C36 D:5IS503 3.6 85.4 1.0
C35 D:5IS503 3.8 86.9 1.0
CZ D:PHE404 3.8 101.1 1.0
C28 D:5IS503 3.8 91.2 1.0
C2 D:5IS503 4.1 85.4 1.0
C4 D:5IS503 4.1 91.6 1.0
C27 D:5IS503 4.1 80.1 1.0
CG1 D:VAL181 4.1 94.3 1.0
CE1 D:PHE404 4.5 107.8 1.0
C3 D:5IS503 4.6 87.8 1.0
CE2 D:PHE404 4.7 100.8 1.0
O32 D:5IS503 4.7 92.0 1.0
CB D:VAL181 4.7 96.0 1.0

Reference:

P.Marzullo, Z.Boiarska, H.Perez-Pena, A.C.Abel, B.Alvarez-Bernad, D.Lucena-Agell, F.Vasile, M.Sironi, K.H.Altmann, A.E.Prota, J.F.Diaz, S.Pieraccini, D.Passarella. Maytansinol Derivatives: Side Reactions As A Chance For New Tubulin Binders. Chemistry 2021.
ISSN: ISSN 0947-6539
PubMed: 34788896
DOI: 10.1002/CHEM.202103520
Page generated: Fri Dec 17 08:42:09 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy