Chlorine »
PDB 5sdc-5sif »
5shl »
Chlorine in PDB 5shl: Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine
Enzymatic activity of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine
All present enzymatic activity of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine:
3.1.4.17;
3.1.4.17;
Protein crystallography data
The structure of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine, PDB code: 5shl
was solved by
C.Joseph,
J.Benz,
A.Flohr,
K.Groebke-Zbinden,
M.G.Rudolph,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 43.45 / 2.35 |
| Space group | H 3 |
| Cell size a, b, c (Å), α, β, γ (°) | 135.094, 135.094, 234.437, 90, 90, 120 |
| R / Rfree (%) | 17.5 / 23.7 |
Other elements in 5shl:
The structure of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine also contains other interesting chemical elements:
| Zinc | (Zn) | 4 atoms |
| Magnesium | (Mg) | 4 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine
(pdb code 5shl). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine, PDB code: 5shl:
Jump to Chlorine binding site number: 1; 2; 3; 4;
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine, PDB code: 5shl:
Jump to Chlorine binding site number: 1; 2; 3; 4;
Chlorine binding site 1 out of 4 in 5shl
Go back to
Chlorine Binding Sites List in 5shl
Chlorine binding site 1 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine within 5.0Å range:
|
Chlorine binding site 2 out of 4 in 5shl
Go back to
Chlorine Binding Sites List in 5shl
Chlorine binding site 2 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine within 5.0Å range:
|
Chlorine binding site 3 out of 4 in 5shl
Go back to
Chlorine Binding Sites List in 5shl
Chlorine binding site 3 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine within 5.0Å range:
|
Chlorine binding site 4 out of 4 in 5shl
Go back to
Chlorine Binding Sites List in 5shl
Chlorine binding site 4 out
of 4 in the Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of Crystal Structure of Human Phosphodiesterase 10 in Complex with 6- Chloro-2,3-Dimethyl-8-Pyrrolidin-1-Ylimidazo[1,2-B]Pyridazine within 5.0Å range:
|
Reference:
A.Flohr,
D.Schlatter,
B.Kuhn,
M.G.Rudolph.
Crystal Structure of A Human Phosphodiesterase 10 Complex To Be Published.
Page generated: Fri Jul 26 16:50:19 2024
Last articles
Zn in 9JPJZn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
