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Chlorine in PDB 5swr: Crystal Structure of PI3KALPHA in Complex with Fragments 20 and 26Enzymatic activity of Crystal Structure of PI3KALPHA in Complex with Fragments 20 and 26
All present enzymatic activity of Crystal Structure of PI3KALPHA in Complex with Fragments 20 and 26:
2.7.1.153; 2.7.11.1; Protein crystallography data
The structure of Crystal Structure of PI3KALPHA in Complex with Fragments 20 and 26, PDB code: 5swr
was solved by
S.B.Gabelli,
B.Vogelstein,
M.S.Miller,
L.M.Amzel,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of PI3KALPHA in Complex with Fragments 20 and 26
(pdb code 5swr). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of PI3KALPHA in Complex with Fragments 20 and 26, PDB code: 5swr: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 5swrGo back to Chlorine Binding Sites List in 5swr
Chlorine binding site 1 out
of 2 in the Crystal Structure of PI3KALPHA in Complex with Fragments 20 and 26
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 5swrGo back to Chlorine Binding Sites List in 5swr
Chlorine binding site 2 out
of 2 in the Crystal Structure of PI3KALPHA in Complex with Fragments 20 and 26
Mono view Stereo pair view
Reference:
M.S.Miller,
S.Maheshwari,
F.M.Mcrobb,
K.W.Kinzler,
L.M.Amzel,
B.Vogelstein,
S.B.Gabelli.
Identification of Allosteric Binding Sites For PI3K Alpha Oncogenic Mutant Specific Inhibitor Design. Bioorg. Med. Chem. V. 25 1481 2017.
Page generated: Sat Dec 12 12:26:48 2020
ISSN: ESSN 1464-3391 PubMed: 28129991 DOI: 10.1016/J.BMC.2017.01.012 |
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