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Chlorine in PDB 5t37: Crystal Structure of Mpges-1 Bound to InhibitorEnzymatic activity of Crystal Structure of Mpges-1 Bound to Inhibitor
All present enzymatic activity of Crystal Structure of Mpges-1 Bound to Inhibitor:
5.3.99.3; Protein crystallography data
The structure of Crystal Structure of Mpges-1 Bound to Inhibitor, PDB code: 5t37
was solved by
J.G.Luz,
S.Antonysamy,
K.Partridge,
M.Fisher,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Mpges-1 Bound to Inhibitor
(pdb code 5t37). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Mpges-1 Bound to Inhibitor, PDB code: 5t37: Chlorine binding site 1 out of 1 in 5t37Go back to Chlorine Binding Sites List in 5t37
Chlorine binding site 1 out
of 1 in the Crystal Structure of Mpges-1 Bound to Inhibitor
Mono view Stereo pair view
Reference:
K.M.Partridge,
S.Antonysamy,
S.N.Bhattachar,
S.Chandrasekhar,
M.J.Fisher,
A.Fretland,
K.Gooding,
A.Harvey,
N.E.Hughes,
S.L.Kuklish,
J.G.Luz,
P.R.Manninen,
J.E.Mcgee,
D.R.Mudra,
A.Navarro,
B.H.Norman,
S.J.Quimby,
M.A.Schiffler,
A.V.Sloan,
A.M.Warshawsky,
J.M.Weller,
J.S.York,
X.P.Yu.
Discovery and Characterization of [(Cyclopentyl)Ethyl]Benzoic Acid Inhibitors of Microsomal Prostaglandin E Synthase-1. Bioorg. Med. Chem. Lett. V. 27 1478 2017.
Page generated: Sat Dec 12 12:27:35 2020
ISSN: ESSN 1464-3405 PubMed: 28190634 DOI: 10.1016/J.BMCL.2016.11.011 |
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