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Chlorine in PDB 5tb8: Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+.
Enzymatic activity of Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+.
All present enzymatic activity of Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+.:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+., PDB code: 5tb8
was solved by
R.Vyas,
Z.Suo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 46.41 / 2.00 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 49.480, 81.400, 53.570, 90.00, 110.28, 90.00 |
| R / Rfree (%) | 18.2 / 23 |
Other elements in 5tb8:
The structure of Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+. also contains other interesting chemical elements:
| Manganese | (Mn) | 6 atoms |
| Sodium | (Na) | 5 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+.
(pdb code 5tb8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+., PDB code: 5tb8:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+., PDB code: 5tb8:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 5tb8
Go back to
Chlorine Binding Sites List in 5tb8
Chlorine binding site 1 out
of 2 in the Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+. within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 5tb8
Go back to
Chlorine Binding Sites List in 5tb8
Chlorine binding site 2 out
of 2 in the Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Precatalytic Ternary Complex of Human Dna Polymerase Beta in Closed Conformation with Gapped Dna Substrate Incoming (-)3TC-Tp and MN2+. within 5.0Å range:
|
Reference:
A.J.Reed,
R.Vyas,
A.T.Raper,
Z.Suo.
Structural Insights Into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed By A Dna Polymerase. J. Am. Chem. Soc. V. 139 465 2017.
ISSN: ESSN 1520-5126
PubMed: 27959534
DOI: 10.1021/JACS.6B11258
Page generated: Fri Jul 26 17:23:16 2024
ISSN: ESSN 1520-5126
PubMed: 27959534
DOI: 10.1021/JACS.6B11258
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