Atomistry » Chlorine » PDB 5t77-5thp » 5tc5
Atomistry »
  Chlorine »
    PDB 5t77-5thp »
      5tc5 »

Chlorine in PDB 5tc5: Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride

Enzymatic activity of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride

All present enzymatic activity of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride:
2.4.2.28;

Protein crystallography data

The structure of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride, PDB code: 5tc5 was solved by S.A.Cameron, R.S.Firestone, V.L.Schramm, S.C.Almo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.00 / 1.96
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 89.522, 121.927, 192.522, 90.00, 90.00, 90.00
R / Rfree (%) 19 / 21.7

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride (pdb code 5tc5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride, PDB code: 5tc5:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 5tc5

Go back to Chlorine Binding Sites List in 5tc5
Chlorine binding site 1 out of 4 in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl302

b:33.6
occ:1.00
 OG1 A:THR197 3.1 31.1 1.0
N A:MET196 3.2 30.9 1.0
N A:THR197 3.5 30.5 1.0
N1' A:BIG301 3.5 28.0 1.0
C2' A:BIG301 3.5 34.5 1.0
CG2 A:THR197 3.5 36.4 1.0
C10 A:BIG301 3.5 22.3 1.0
OG1 A:THR93 3.7 34.3 1.0
CB A:ASN195 3.7 29.2 1.0
O A:HOH472 3.8 44.5 1.0
CB A:THR197 3.8 33.2 1.0
CA A:MET196 3.8 31.6 1.0
C A:MET196 3.9 33.7 1.0
CB A:MET196 4.0 32.3 1.0
CG A:ASN195 4.0 29.9 1.0
ND2 A:ASN195 4.0 28.9 1.0
C A:ASN195 4.2 30.8 1.0
O A:ALA94 4.2 27.8 1.0
CA A:THR197 4.3 33.1 1.0
O3' A:BIG301 4.3 41.8 1.0
CA A:ASN195 4.3 29.0 1.0
C3' A:BIG301 4.5 35.3 1.0
CG A:MET196 4.7 31.5 1.0
OD1 A:ASN195 4.8 29.7 1.0
C9 A:BIG301 4.9 31.9 1.0
CB A:THR93 4.9 35.8 1.0
C1' A:BIG301 4.9 28.1 1.0
O A:MET196 4.9 29.5 1.0

Chlorine binding site 2 out of 4 in 5tc5

Go back to Chlorine Binding Sites List in 5tc5
Chlorine binding site 2 out of 4 in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl303

b:29.5
occ:1.00
 O C:HOH470 2.5 39.6 1.0
NH1 C:ARG116 3.2 28.1 1.0
NH1 A:ARG116 3.2 28.2 1.0
NH1 B:ARG116 3.2 27.7 1.0
CD C:ARG116 3.9 29.8 1.0
CD A:ARG116 3.9 30.4 1.0
CD B:ARG116 3.9 28.6 1.0
CH2 C:TRP189 4.2 29.6 1.0
CZ C:ARG116 4.3 30.1 1.0
CZ B:ARG116 4.3 28.3 1.0
CZ A:ARG116 4.3 27.7 1.0
CH2 B:TRP189 4.4 30.6 1.0
CH2 A:TRP189 4.4 28.1 1.0
O B:HOH436 4.4 40.3 1.0
NE C:ARG116 4.6 27.9 1.0
NE A:ARG116 4.6 26.7 1.0
NE B:ARG116 4.6 27.7 1.0
CZ3 C:TRP189 4.9 28.8 1.0
CZ3 B:TRP189 4.9 29.8 1.0

Chlorine binding site 3 out of 4 in 5tc5

Go back to Chlorine Binding Sites List in 5tc5
Chlorine binding site 3 out of 4 in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl302

b:34.8
occ:1.00
 OG1 B:THR197 3.0 33.8 1.0
N B:MET196 3.2 31.3 1.0
CG2 B:THR197 3.5 37.1 1.0
N B:THR197 3.5 32.6 1.0
C2' B:BIG301 3.6 35.0 1.0
N1' B:BIG301 3.7 33.8 1.0
OG1 B:THR93 3.7 38.2 1.0
C10 B:BIG301 3.7 26.0 1.0
CB B:THR197 3.7 36.6 1.0
CB B:ASN195 3.8 30.9 1.0
CA B:MET196 3.9 32.9 1.0
C B:MET196 3.9 34.1 1.0
CB B:MET196 4.0 33.0 1.0
ND2 B:ASN195 4.1 31.8 1.0
CG B:ASN195 4.1 31.1 1.0
O B:HOH456 4.2 40.2 1.0
O B:ALA94 4.2 33.4 1.0
CA B:THR197 4.3 33.7 1.0
C B:ASN195 4.3 31.0 1.0
CA B:ASN195 4.4 29.8 1.0
C3' B:BIG301 4.7 35.1 1.0
CG B:MET196 4.7 32.3 1.0
O3' B:BIG301 4.8 44.8 1.0
OD1 B:ASN195 4.9 31.3 1.0
CB B:THR93 4.9 40.2 1.0
O B:MET196 5.0 31.9 1.0

Chlorine binding site 4 out of 4 in 5tc5

Go back to Chlorine Binding Sites List in 5tc5
Chlorine binding site 4 out of 4 in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Butylthio-Dadme-Immucillin-A and Chloride within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl302

b:38.8
occ:1.00
 OG1 C:THR197 3.1 34.3 1.0
N C:MET196 3.2 33.1 1.0
O C:HOH466 3.3 51.4 1.0
CG2 C:THR197 3.5 41.4 1.0
N1' C:BIG301 3.6 34.9 1.0
N C:THR197 3.6 34.0 1.0
C2' C:BIG301 3.6 38.8 1.0
C10 C:BIG301 3.6 26.6 1.0
OG1 C:THR93 3.6 35.6 1.0
CB C:ASN195 3.6 30.1 1.0
CB C:THR197 3.8 37.2 1.0
CA C:MET196 3.9 33.6 1.0
ND2 C:ASN195 4.0 30.5 1.0
CG C:ASN195 4.0 29.4 1.0
C C:MET196 4.0 34.4 1.0
CB C:MET196 4.0 35.3 1.0
O C:ALA94 4.2 32.5 1.0
C C:ASN195 4.2 31.1 1.0
CA C:ASN195 4.3 28.7 1.0
CA C:THR197 4.3 35.3 1.0
O3' C:BIG301 4.5 57.0 1.0
C3' C:BIG301 4.5 40.7 1.0
CG C:MET196 4.7 33.8 1.0
OD1 C:ASN195 4.8 28.9 1.0
CB C:THR93 4.9 36.5 1.0
C9 C:BIG301 4.9 32.1 1.0
O C:MET196 5.0 35.0 1.0

Reference:

R.S.Firestone, S.A.Cameron, J.M.Karp, V.L.Arcus, V.L.Schramm. Tba To Be Published.
Page generated: Fri Jul 26 17:23:49 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy