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Chlorine in PDB 5tc6: Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Propylthio-Immucillin-A

Enzymatic activity of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Propylthio-Immucillin-A

All present enzymatic activity of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Propylthio-Immucillin-A:
2.4.2.28;

Protein crystallography data

The structure of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Propylthio-Immucillin-A, PDB code: 5tc6 was solved by S.A.Cameron, R.S.Firestone, V.L.Schramm, S.C.Almo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.00 / 1.48
Space group P 3 2 1
Cell size a, b, c (Å), α, β, γ (°) 122.760, 122.760, 44.484, 90.00, 90.00, 120.00
R / Rfree (%) 16.7 / 18.5

Other elements in 5tc6:

The structure of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Propylthio-Immucillin-A also contains other interesting chemical elements:

Sodium (Na) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Propylthio-Immucillin-A (pdb code 5tc6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Propylthio-Immucillin-A, PDB code: 5tc6:

Chlorine binding site 1 out of 1 in 5tc6

Go back to Chlorine Binding Sites List in 5tc6
Chlorine binding site 1 out of 1 in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Propylthio-Immucillin-A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with Propylthio-Immucillin-A within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl305

b:12.8
occ:0.33
O A:HOH609 3.0 20.7 0.3
NH1 A:ARG116 3.2 11.5 1.0
CD A:ARG116 3.8 10.9 1.0
CH2 A:TRP189 4.2 14.2 1.0
CZ A:ARG116 4.3 11.2 1.0
O A:HOH568 4.4 18.2 1.0
NE A:ARG116 4.5 10.8 1.0
CZ3 A:TRP189 4.9 14.4 1.0
CZ2 A:TRP189 4.9 14.0 1.0

Reference:

R.S.Firestone, S.A.Cameron, J.M.Karp, V.L.Arcus, V.L.Schramm. Tba To Be Published.
Page generated: Fri Jul 26 17:24:02 2024

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