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Chlorine in PDB 5tc7: Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with 5'-Methylthiotubercidin at 1.75 Angstrom

Enzymatic activity of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with 5'-Methylthiotubercidin at 1.75 Angstrom

All present enzymatic activity of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with 5'-Methylthiotubercidin at 1.75 Angstrom:
2.4.2.28;

Protein crystallography data

The structure of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with 5'-Methylthiotubercidin at 1.75 Angstrom, PDB code: 5tc7 was solved by S.A.Cameron, R.S.Firestone, V.L.Schramm, S.C.Almo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.00 / 1.75
Space group P 3 2 1
Cell size a, b, c (Å), α, β, γ (°) 123.359, 123.359, 44.499, 90.00, 90.00, 120.00
R / Rfree (%) 17 / 18.4

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with 5'-Methylthiotubercidin at 1.75 Angstrom (pdb code 5tc7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with 5'-Methylthiotubercidin at 1.75 Angstrom, PDB code: 5tc7:

Chlorine binding site 1 out of 1 in 5tc7

Go back to Chlorine Binding Sites List in 5tc7
Chlorine binding site 1 out of 1 in the Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with 5'-Methylthiotubercidin at 1.75 Angstrom


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with 5'-Methylthiotubercidin at 1.75 Angstrom within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl305

b:18.6
occ:0.33
O A:HOH575 3.1 62.0 0.3
NH1 A:ARG116 3.3 18.6 1.0
CD A:ARG116 3.8 17.3 1.0
CH2 A:TRP189 4.3 19.9 1.0
CZ A:ARG116 4.3 18.0 1.0
O A:HOH545 4.4 24.2 1.0
NE A:ARG116 4.5 17.4 1.0
CZ3 A:TRP189 4.9 20.6 1.0

Reference:

R.S.Firestone, S.A.Cameron, J.M.Karp, V.L.Arcus, V.L.Schramm. Tba To Be Published.
Page generated: Fri Jul 26 17:24:16 2024

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